What vaccinations are recommended for an 18-year-old male?

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Last updated: August 20, 2025View editorial policy

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Recommended Vaccinations for an 18-Year-Old Male

An 18-year-old male should receive the influenza vaccine annually, a Tdap booster if not previously administered at age 11-12, MenACWY vaccine if not received after age 16, and consideration for HPV and MenB vaccines based on risk factors and previous vaccination status. 1

Core Recommended Vaccines

Influenza Vaccine

  • Annual vaccination with the current seasonal influenza vaccine
  • Can be administered regardless of egg allergy history 1

Tetanus, Diphtheria, and Pertussis (Tdap)

  • One dose of Tdap if not previously received during adolescence (ages 11-12)
  • If Tdap was already administered, no additional dose is needed at this time 1

Meningococcal Conjugate Vaccine (MenACWY)

  • One dose of MenACWY if not received on or after the 16th birthday
  • Particularly important for first-year college students living in residence halls 1
  • Military recruits should receive a single dose of MenACWY 1

Human Papillomavirus (HPV) Vaccine

  • Complete 3-dose series if not previously vaccinated or series is incomplete
  • For males aged 18-21 years who have not been previously vaccinated or who have not completed the series
  • Recommended through age 26 years for men who have sex with men or who are immunocompromised 1
  • Dosing schedule: 0,1-2 months, and 6 months 1

Meningococcal B Vaccine (MenB)

  • May be administered to young adults aged 16-23 years (preferred age 16-18 years) based on shared clinical decision-making
  • Options include either a 2-dose series of MenB-4C at least 1 month apart or a 2-dose series of MenB-FHbp at 0 and 6 months 1, 2
  • Particularly important to consider for college students due to outbreaks on college campuses 2

Special Situations Requiring Additional Vaccines

For High-Risk Individuals

  • Anatomical or functional asplenia: MenACWY (2-dose primary series at least 2 months apart with revaccination every 5 years) and MenB series 1
  • Persistent complement component deficiencies: MenACWY and MenB series 1, 2
  • HIV infection: MenACWY (2-dose primary series at least 2 months apart with revaccination every 5 years) 1
  • Microbiologists routinely exposed to N. meningitidis: MenACWY and MenB series 1
  • International travel to regions with hyperendemic/epidemic meningococcal disease: MenACWY with revaccination every 5 years if risk continues 1

For College Students

  • First-year college students aged ≤21 years living in residence halls should receive MenACWY if not vaccinated on or after their 16th birthday 1, 2
  • Consider MenB vaccination based on shared clinical decision-making, particularly given the 200-1400-fold increased risk of meningococcal disease during outbreaks 2

Practical Considerations

Concomitant Administration

  • Multiple vaccines can be administered during the same visit at different anatomical sites 2, 3, 4
  • Studies show that HPV, Tdap, and MenACWY vaccines can be administered together without decreased immunogenicity or increased reactogenicity 3, 4

Common Pitfalls to Avoid

  1. Missing the MenACWY booster: Only 23.2% of adolescents complete both the primary and booster doses of MenACWY 5
  2. Overlooking HPV vaccination: Many males do not complete the HPV series, which protects against genital warts and HPV-related cancers
  3. Failing to assess risk factors: Special populations may need additional vaccines or different dosing schedules
  4. Not checking vaccination history: Verify previous doses to avoid unnecessary revaccination or missed opportunities

Vaccination Documentation

  • Document all administered vaccines in the patient's medical record
  • Encourage registration with state or regional Immunization Information Systems
  • Provide the patient with documentation of vaccines received and recommended follow-up doses

By ensuring appropriate vaccination coverage for 18-year-old males, healthcare providers can significantly reduce the risk of vaccine-preventable diseases that cause substantial morbidity and mortality in this age group.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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