Recommended Approach for a Neurological Examination
A comprehensive neurological examination should include assessment of mental status, cranial nerve function, motor function, coordination, sensation, reflexes, and gait, using standardized tools whenever feasible. 1
Core Components of the Neurological Examination
1. Mental Status Assessment
- Use standardized scoring tools such as the Glasgow Coma Scale 2
- Assess cognitive domains including:
- Learning and memory (particularly delayed free and cued recall/recognition)
- Attention
- Executive function
- Visuospatial function
- Language 2
- Consider using the Confusion Assessment Method for delirium screening 2
2. Cranial Nerve Examination
- Assess pupillary light response
- Evaluate eye movements (pursuit and saccades)
- Test facial strength
- Assess tongue movements
- Evaluate cough/gag reflexes 2
3. Motor Examination
- Assess muscle tone in arms and legs
- Evaluate muscle strength using the Medical Research Council scale
- Test for pronator drift or rapid arm movements in upper limbs
- Look for abnormal movements or tremors 3
4. Coordination Testing
5. Sensory Examination
- Test light touch, pinprick, temperature, vibration, and proprioception
- Pay special attention to distal-to-proximal gradient in suspected peripheral neuropathies 4
6. Reflex Testing
- Assess deep tendon reflexes (biceps, triceps, brachioradialis, patellar, and Achilles)
- Test plantar responses (Babinski sign) 3
7. Gait and Station Assessment
- Observe natural walking pattern
- Test tandem gait
- Assess Romberg test
- Evaluate for specific gait patterns:
- Wide-based cerebellar ataxia
- Waddling gait
- Vestibular dysfunction 1
Specialized Considerations
For Suspected Ataxia
- Focus on coordination tests
- Evaluate for truncal ataxia (difficulty sitting/standing without support)
- Distinguish between cerebellar and sensory ataxia (the latter worsens with eyes closed) 1
For Suspected Cognitive Impairment
- Perform more detailed cognitive assessment
- Consider neuropsychological evaluation when office-based cognitive assessment is not sufficiently informative 2
- Include assessment of behavioral symptoms using tools like the Neuropsychiatric Inventory-Q 2
- Evaluate functional abilities using scales like the Pfeffer Functional Assessment Questionnaire or Barthel Index 2
For Critically Ill Patients
- Manage sedation appropriately to maximize detection of neurological dysfunction
- Perform serial examinations to detect changes
- Consider additional neurophysiological and neuroradiological investigations based on examination findings 5
Documentation and Monitoring
- Establish a baseline neurological assessment
- Perform serial evaluations to monitor for changes
- Document findings using standardized formats
- Consider the frequency of reassessment based on clinical context and risk 2, 6
Common Pitfalls to Avoid
- Failing to perform a complete examination due to time constraints
- Not using standardized assessment tools
- Misattributing neurological signs due to incomplete assessment 1
- Overlooking subtle neurological deficits
- Inadequate documentation of baseline status for future comparison 6
By following this structured approach to the neurological examination, clinicians can effectively detect neurological dysfunction, establish appropriate diagnoses, and monitor disease progression or treatment response.