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Differential Diagnosis for Sores in Between Toes and Peeling Feet

Single Most Likely Diagnosis

  • Tinea Pedis (Athlete's Foot): This is the most common fungal infection of the foot, characterized by itching, burning, and cracking of the skin, especially between the toes. The peeling of feet is also a hallmark of this condition, making it the top differential diagnosis.

Other Likely Diagnoses

  • Eczema (Dyshidrotic Eczema): This condition presents with small, itchy blisters on the feet, which can lead to peeling and sores, especially between the toes.
  • Contact Dermatitis: An allergic reaction or irritation from substances like soap, detergent, or certain materials in shoes can cause skin peeling and sores on the feet.
  • Psoriasis: Although less common on the feet, psoriasis can cause red, scaly patches and peeling, potentially leading to sores if the skin cracks.

Do Not Miss Diagnoses

  • Diabetic Foot Ulcers: In patients with diabetes, sores between the toes can be a sign of a diabetic foot ulcer, which requires immediate medical attention to prevent serious complications like infection and amputation.
  • Cellulitis: A bacterial infection of the skin that can start as a small, red area and spread, potentially causing sores and peeling. It's crucial to diagnose and treat promptly to avoid severe consequences.
  • Deep Vein Thrombosis (DVT): Although DVT typically presents with swelling and pain in one leg, in rare cases, it can cause skin changes, including peeling and sores, especially if there's associated venous insufficiency.

Rare Diagnoses

  • Pitted Keratolysis: A bacterial infection that causes small pits and cracks in the skin of the feet, potentially leading to peeling and sores.
  • Keratoderma: A group of rare genetic disorders that cause thickening of the skin on the feet, which can lead to peeling and sores.
  • Lymphoma: Certain types of lymphoma can cause skin lesions, including on the feet, though this would be an extremely rare presentation.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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