Management of Appendicitis in Pregnant Patients
For pregnant patients with ultrasound-confirmed appendicitis, prompt surgical consultation and laparoscopic appendectomy is the recommended management approach, as it reduces maternal and fetal morbidity and mortality.
Diagnostic Approach
- For pregnant patients with suspected appendicitis, abdominal ultrasound should be used as the initial imaging modality 1
- If ultrasound results are equivocal or non-diagnostic but clinical suspicion persists, MRI is the preferred next imaging modality to avoid radiation exposure 1
- Short observation periods with repeated ultrasound in pregnant patients with equivocal appendicitis is acceptable and does not appear to increase maternal or fetal adverse outcomes 1
Surgical Management
- Laparoscopic appendectomy is the gold standard treatment for pregnant patients with confirmed appendicitis 2
- Surgery should be performed within 24 hours of admission to minimize complications 1
- Delaying appendectomy beyond 24 hours from admission is associated with increased risk of adverse outcomes 1
Antibiotic Therapy
- All patients with appendicitis should receive appropriate antimicrobial therapy 1
- Recommended regimens include:
- Amoxicillin/clavulanate
- Ceftriaxone + metronidazole
- Cefotaxime + metronidazole 2
Special Considerations in Pregnancy
- Laparoscopic approach is preferred over open appendectomy in pregnant patients when surgery is indicated 2
- Pregnant patients require special attention to:
- Positioning during surgery (left lateral tilt to avoid vena cava compression)
- Lower insufflation pressures during laparoscopy
- Fetal monitoring before and after the procedure
- Consultation with obstetrics
Timing Considerations
- Appendicitis in pregnancy is a surgical emergency requiring prompt intervention
- Significant increase in the likelihood of perforated appendicitis occurs after 72 hours of symptoms 1
- Delaying surgery increases risks of maternal morbidity and potential fetal loss
Potential Complications
- Perforation rates are higher in pregnant patients due to anatomical changes and potential diagnostic delays
- Perforation can lead to sepsis in 17-32% of patients with acute appendicitis 3
- Maternal complications include wound infections and intra-abdominal abscesses
- Fetal complications include preterm labor and, in severe cases, fetal loss
Follow-up Care
- Close monitoring for postoperative complications
- Obstetric follow-up to monitor fetal wellbeing
- Wound care and pain management appropriate for pregnancy
The management of appendicitis in pregnancy requires a coordinated approach between emergency medicine, surgery, and obstetrics to ensure optimal outcomes for both mother and fetus.