Treatment for Costochondritis
For costochondritis, a short-term course of nonsteroidal anti-inflammatory drugs (NSAIDs) for 1-2 weeks is the first-line treatment, with the addition of low-dose colchicine as needed for persistent symptoms. 1
First-Line Pharmacological Treatment
NSAIDs:
Acetaminophen (Paracetamol):
Second-Line or Adjunctive Treatments
Colchicine:
- May be added to NSAIDs for persistent inflammatory symptoms 1
- Low-dose regimen (0.5-1.0 mg daily)
Topical Analgesics:
- Topical NSAIDs can provide localized pain relief with fewer systemic effects 3
- Apply to affected area 3-4 times daily
Non-Pharmacological Approaches
Activity Modification:
- Avoid activities that exacerbate symptoms 2
- Rest from activities that involve chest muscle overuse
Stretching Exercises:
- Progressive stretching exercises have shown significant improvement in pain compared to conventional treatment alone 4
- Focus on gentle stretching of chest wall muscles and improving thoracic mobility
Manual Therapy:
- Manipulative therapy and soft tissue mobilization may be beneficial for persistent cases 5
- Instrument-assisted soft tissue mobilization has shown promise in atypical costochondritis
Heat Application:
- Local heat application can help reduce pain and muscle tension 4
Treatment Algorithm
Initial Presentation:
- Rule out serious causes of chest pain (cardiac, pulmonary, etc.)
- Confirm diagnosis through reproduction of pain with palpation of costochondral junctions
First 1-2 Weeks:
- Start NSAIDs (if no contraindications)
- Advise activity modification and rest
- Apply local heat
If Inadequate Response After 2 Weeks:
- Consider adding low-dose colchicine
- Implement stretching exercises
- Consider referral for manual therapy techniques
For Persistent Cases (>4-6 Weeks):
- Re-evaluate diagnosis
- Consider physical therapy referral for specialized manual techniques and exercise prescription
- Evaluate for atypical costochondritis
Special Considerations
Infectious Costochondritis:
- Rare but requires different management with antibiotics and possible surgical debridement 6
- Suspect if fever, purulent discharge, or systemic symptoms are present
Elderly Patients or Those with Cardiovascular Risk Factors:
- Cardiac causes must be ruled out before diagnosing costochondritis 2
- ECG and possibly chest radiograph should be obtained in patients >35 years or with cardiovascular risk factors
Prognosis
Most cases of costochondritis are self-limiting and resolve within weeks to months with appropriate treatment. Atypical cases that persist beyond this timeframe may benefit from specialized physical therapy interventions 5.
The key to successful management is early appropriate treatment with anti-inflammatory medications, activity modification, and progressive introduction of stretching exercises as symptoms improve.