Management Plan for a 68-Year-Old Man with History of Stroke
The optimal management plan for a 68-year-old man with a history of stroke should focus on comprehensive secondary prevention strategies that address all modifiable risk factors, consistent with national guidelines, to reduce mortality, maximize recovery, and prevent recurrent stroke and cardiovascular events. 1
Secondary Prevention Strategies
Antithrombotic Therapy
For noncardioembolic ischemic stroke:
- Prescribe one of the following antiplatelet agents:
- Aspirin 50-325 mg daily
- Clopidogrel 75 mg daily
- Combination aspirin 25 mg/dipyridamole 200 mg twice daily 1
- For recent minor stroke (within 21-90 days), consider short-term dual antiplatelet therapy (aspirin plus clopidogrel) followed by single antiplatelet therapy 1
- Prescribe one of the following antiplatelet agents:
For cardioembolic stroke (if atrial fibrillation is present):
- Prescribe oral anticoagulation unless contraindicated
- Prefer direct oral anticoagulants (apixaban, dabigatran, edoxaban, or rivaroxaban) over warfarin except for patients with moderate to severe mitral stenosis or mechanical heart valves 1
Blood Pressure Management
- Target blood pressure <130/80 mmHg
- Implement lifestyle modifications and pharmacological therapy as needed
- Select appropriate antihypertensive medications based on comorbidities and patient-specific factors 1
Lipid Management
- Prescribe high-intensity statin therapy (atorvastatin or rosuvastatin) to reduce LDL-C by ≥50%
- Target LDL-C <70 mg/dL for high-risk patients, including those with aortic arch atheroma 1
Lifestyle Modifications
- Counsel on a Mediterranean-type diet high in vegetables, fruits, whole grains, fish, nuts, and olive oil 1
- Encourage regular physical activity appropriate to the patient's functional capacity
- Recommend smoking cessation if applicable
- Advise limited alcohol consumption
- Support weight management if overweight or obese 1
Diabetes Management
- For patients with diabetes, optimize glycemic control with target HbA1c individualized based on age, comorbidities, and life expectancy
- Consider referral to endocrinology for complex cases
Functional Assessment and Rehabilitation
Neurological Assessment
- Screen for residual neurological impairments:
- Cognitive evaluation
- Depression screening
- Assessment of fitness to drive
- Evaluation of activities of daily living 1
Rehabilitation Services
- Refer to appropriate rehabilitation specialists for any identified neurological impairments or functional limitations 1
- Ensure access to a coordinated multidisciplinary rehabilitation team experienced in stroke care 1
- Consider the severity of impairment, availability of family/social support, and patient/family preferences when determining the optimal environment for rehabilitation 1
Long-term Functional Support
- Provide a home exercise program or refer to an appropriate community exercise program
- Recommend regular strengthening and aerobic exercise designed with consideration of comorbidities and functional limitations 1
- Assess need for assistive devices, adaptive equipment, mobility aids, or orthoses 1
Follow-up Care
Medical Follow-up
- Schedule follow-up with primary care provider within 1 month of discharge 1
- Arrange follow-up with rehabilitation professionals 3-6 months after discharge if rehabilitation services were provided 1
- Ensure comprehensive screening for post-acute complications 1
Care Coordination
- Establish support systems to ensure appropriate follow-up with specialized stroke services and primary care 1
- Provide education and training for the patient and family members 1
- Ensure clear, comprehensive, and timely communication across the inpatient and outpatient poststroke continuum of care 1
Secondary Prevention Education
- Educate patient and family about stroke risk factors and prevention strategies 1
- Provide individualized information and counseling about lifestyle modifications 1
- Reinforce self-management of stroke risk factors and lifestyle changes 1
Addressing Social Determinants of Health
- Assess and address factors such as literacy level, language proficiency, medication affordability, food insecurity, housing, and transportation 1
- Ensure that oral instructions are understandable and sensitive to health literacy 1
Common Pitfalls and Caveats
- Avoid focusing solely on one aspect of care (e.g., medications) while neglecting other important components like lifestyle modifications and rehabilitation
- Don't overlook screening for depression, which is common after stroke and can impede recovery
- Ensure that the patient is not lost to follow-up after discharge from acute or rehabilitation services
- Remember that secondary prevention is lifelong and requires ongoing monitoring and adjustment of interventions
By implementing this comprehensive management plan, the risk of recurrent stroke and other cardiovascular events can be significantly reduced while maximizing functional recovery and quality of life for this 68-year-old man with a history of stroke.