Differential Diagnosis for Not Passing Meconium
- Single Most Likely Diagnosis
- Cystic Fibrosis: This is a common cause of intestinal obstruction in newborns due to the thick, sticky meconium that can block the intestines. It's an important diagnosis to consider because early intervention can improve outcomes.
- Other Likely Diagnoses
- Hirschsprung's Disease: A congenital condition characterized by the absence of ganglion cells in the distal bowel, leading to a functional obstruction. It's a common cause of failure to pass meconium within the first 48 hours of life.
- Intestinal Atresia: A congenital anomaly where there's a complete or partial obstruction of the intestine, which can prevent the passage of meconium.
- Meconium Ileus: A condition where the meconium in the intestine is thicker and stickier than normal, causing a blockage. It's often associated with cystic fibrosis.
- Do Not Miss Diagnoses
- Intestinal Volvulus: A condition where the intestine twists around itself, cutting off blood supply. It's a surgical emergency that requires prompt intervention to prevent tissue death.
- Necrotizing Enterocolitis: A serious condition where a portion of the bowel tissue dies due to lack of blood supply. It's more common in premature infants but can occur in term babies as well.
- Rare Diagnoses
- Congenital Aganglionic Megacolon (Total Intestinal Aganglionosis): A rare form of Hirschsprung's disease where the entire intestine lacks ganglion cells.
- Chronic Intestinal Pseudo-Obstruction: A rare condition characterized by recurrent episodes of intestinal obstruction without any mechanical cause.
- Meconium Plug Syndrome: A rare condition where a plug of meconium blocks the intestine, often associated with maternal diabetes or other maternal medical conditions.