What stage of pressure injury is characterized by a bullae (fluid-filled blister) containing blood?

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Blood-Filled Bullae in Pressure Injuries: Staging Classification

A pressure injury with a blood-filled bullae (fluid-filled blister containing blood) is classified as a Stage 2 pressure injury. 1

Understanding Stage 2 Pressure Injuries

Stage 2 pressure injuries are characterized by:

  • Partial-thickness loss of dermis
  • Present as a shallow open ulcer with a red-pink wound bed without slough
  • May also present as an intact or ruptured serum-filled blister 2

When the fluid within the blister contains blood (hemorrhagic bullae), this remains classified as a Stage 2 pressure injury, as the damage is still limited to the dermis and has not extended to deeper tissues.

Distinguishing Features of Stage 2 Pressure Injuries

  • Involves only the epidermis and part of the dermis
  • Does not extend to subcutaneous fat
  • May present as an intact blister or shallow open ulcer
  • The wound bed appears red-pink and viable 1

Differential Considerations

It's important to distinguish blood-filled bullae in pressure injuries from other conditions:

  • Necrotizing fasciitis: Blood-filled bullae can also be a sign of necrotizing fasciitis, which is a medical emergency requiring immediate surgical intervention 3
  • Deep tissue pressure injury (DTPI): These appear as purple or maroon localized areas of discolored intact skin or blood-filled blisters due to damage of underlying soft tissue from pressure and/or shear
  • Stage 3 pressure injury: These involve full-thickness tissue loss extending into the subcutaneous fat 1

Clinical Implications

The presence of blood in a pressure injury blister requires careful assessment:

  • Blood-filled bullae may indicate trauma to the tissue or capillary damage
  • The area should be monitored closely for signs of deterioration
  • Blood-filled bullae should not be confused with deep tissue pressure injury, which presents as purple or maroon discoloration of intact skin 2

Management Approach

  1. Assessment: Carefully document the size, location, and characteristics of the blood-filled bullae
  2. Wound care:
    • Keep the area clean and protected
    • If the blister is intact, consider leaving it in place as a natural barrier
    • If broken, clean the area and apply appropriate dressing 1
  3. Pressure redistribution: Implement repositioning schedule and use pressure-redistributing surfaces 1
  4. Monitor for infection: Watch for signs of local infection or deeper tissue involvement 2
  5. Nutritional support: Ensure adequate protein intake (1.25-1.5 g/kg/day) to support wound healing 1

Prevention of Progression

To prevent progression to deeper stage injuries:

  • Implement a turning schedule every 2 hours
  • Use specialized pressure-redistributing surfaces
  • Maintain optimal nutrition and hydration
  • Perform regular skin assessments 1

Common Pitfalls

  • Misclassifying blood-filled bullae as deep tissue injury when they are actually Stage 2
  • Failing to distinguish between pressure-related blood-filled bullae and those caused by other conditions like necrotizing fasciitis
  • Neglecting to assess for biofilm formation and infection, which can hinder healing 1
  • Inadequate pressure redistribution leading to worsening of the injury

Remember that accurate staging is essential for appropriate treatment planning and documentation. Blood-filled bullae in pressure injuries should be monitored closely for signs of deterioration to deeper tissue involvement.

References

Guideline

Pressure Sore Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Hemorrhagic bullae are not only skin deep.

The American journal of emergency medicine, 2008

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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