What are the characteristics of intussusception in adults?

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Surgical Management of Adult Intussusception

Adult intussusception usually requires surgical resection due to the high likelihood of pathological lead points, with 92-94% of cases having an underlying lesion, often malignant in colonic cases. 1, 2

Characteristics of Adult Intussusception

Adult intussusception differs significantly from pediatric cases in several key ways:

  • Etiology: Unlike pediatric cases which are typically idiopathic, adult intussusception is associated with a pathological lead point in 92-94% of cases 2, 3
  • Frequency: Represents only 1% of all bowel obstructions, 5% of all intussusceptions, and 0.003%-0.02% of all hospital admissions 4
  • Presentation: Most commonly presents with intestinal obstruction (71% of cases) 2
  • Distribution: Occurs more frequently in the small intestine (76.9%) than colon (15.4%) or ileocecal valve (7.7%) 3

Diagnostic Approach

Diagnosis is often challenging due to variable and non-specific symptoms:

  • CT scan: Most accurate diagnostic tool with 90% accuracy 2
  • Ultrasonography: 78.5% diagnostic accuracy 2
  • Colonoscopy: 100% accuracy for ileocolic and colonic intussusception 2

Treatment Strategy

Small Bowel Intussusception

  • Lead point risk factors: Age >60 years (RR 2.2), history of malignancy (RR 3.7), and mass on CT (RR 2.9) significantly increase likelihood of pathological lead point 5
  • Approach: Reduction before resection may be attempted if:
    • Underlying etiology is suspected to be benign
    • Resection without reduction would require extensive bowel removal 2
    • No evidence of strangulation or perforation 3

Colonic Intussusception

  • Approach: En-bloc resection without reduction is recommended due to:
    • High malignancy rate (43-70% of cases) 1, 3, 4
    • Risk of perforation and spillage of malignant cells 3

Retrograde Intussusception

  • Typically does not have a lead point 5
  • May be managed more conservatively

Outcomes and Prognosis

  • Surgical mortality is low when properly managed 3
  • Recurrence is uncommon after appropriate surgical management
  • Hydrostatic reduction, which is commonly used in pediatric cases, is not typically effective in adults due to the high prevalence of pathological lead points 6

Common Pitfalls to Avoid

  • Delayed diagnosis: Intussusception in adults presents with variable symptoms and can be easily missed; maintain high index of suspicion
  • Inappropriate reduction: Attempting reduction in colonic intussusception risks perforation and tumor seeding
  • Overlooking incidental findings: Transient, asymptomatic intussusceptions found on imaging may be observed without intervention 6
  • Assuming idiopathic cause: Unlike in children, adult intussusception is rarely idiopathic and underlying pathology should always be suspected

The answer to the multiple-choice question is (b) - adult intussusception usually requires resection due to the high likelihood of pathological lead points, particularly in colonic cases where malignancy is common.

References

Guideline

Surgical Management of Intussusception

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Intussusception in adults: institutional review.

International journal of surgery (London, England), 2011

Research

Intussusception in adults: an unusual and challenging condition for surgeons.

International journal of colorectal disease, 2005

Research

Adult intussusception.

Annals of surgery, 1997

Research

Intestinal Intussusception: Etiology, Diagnosis, and Treatment.

Clinics in colon and rectal surgery, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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