Lichen sclerosus: This condition is a common cause of vulvar pruritus, especially in postmenopausal women. It is characterized by thinning of the vulvar skin, which can lead to intense itching.

Lichen planus: An inflammatory condition that can affect the vulva, causing pruritus, pain, and white, lacy patches on the skin.
Vulvar dermatitis (eczema): A condition that can cause itching, redness, and skin thickening due to allergic reactions or irritants.
Vulvovaginal candidiasis: A yeast infection that can cause itching, burning, and abnormal discharge.
Psoriasis: A chronic skin condition that can affect the vulva, leading to itching, redness, and scaly patches.

Vulvar intraepithelial neoplasia (VIN) or vulvar cancer: Although less common, these conditions can present with persistent vulvar pruritus and must be ruled out to avoid delayed diagnosis and treatment.
Invasive infections (e.g., herpes simplex virus, syphilis): These infections can cause severe symptoms, including pruritus, and require prompt treatment to prevent complications.
Systemic diseases (e.g., diabetes, renal failure, liver disease): Certain systemic conditions can cause vulvar pruritus as a symptom, and identifying the underlying disease is crucial for proper management.

Neurological disorders (e.g., neuropathic pruritus, vulvodynia): These conditions can cause chronic vulvar pruritus without an identifiable skin lesion.
Contact dermatitis due to unusual allergens (e.g., metals, chemicals): Rare allergens can cause vulvar dermatitis and pruritus in susceptible individuals.
Erythema multiforme: A rare skin condition that can affect the vulva, causing itching, burning, and target-like lesions.
Langerhans cell histiocytosis: A rare disorder that can cause vulvar lesions and pruritus, often in children.