Treatment for Bug Bites
The first-line treatment for bug bites includes removing any stinger immediately, cleaning the wound with soap and water, and applying cold compresses, oral antihistamines, and topical hydrocortisone for symptom relief. 1, 2
Immediate Management
Wound Care:
Symptom Management:
Special Considerations
Allergic Reactions
- Monitor for signs of allergic reactions, which may require immediate medical attention 1
- For systemic allergic reactions:
- Administer intramuscular epinephrine as first-line treatment (0.3-0.5 mg in adults, 0.01 mg/kg up to 0.3 mg in children) 1
- H1 antihistamines, H2 antihistamines, and corticosteroids may help with symptoms but should never replace epinephrine 1
- Observe patients for at least 4-6 hours after anaphylaxis treatment 1
Infection Prevention
- Tetanus prophylaxis is not routinely needed after simple insect stings unless tetanus vaccination is not current 1
- Routine antibiotic prophylaxis is not indicated for uncomplicated insect stings 1
- Consider preemptive antibiotic therapy (3-5 days) for:
- Immunocompromised patients
- Asplenic patients
- Patients with advanced liver disease
- Moderate to severe injuries, especially to hand or face 1
Antihistamine Selection
While the guideline mentions antihistamines generally, research evidence suggests:
- Cetirizine and levocetirizine appear most effective for reducing both immediate and delayed mosquito bite reactions 3, 4
- Levocetirizine 5mg decreased wheal size by 60% and pruritus by 62%, with greater effect in those with larger bite reactions 4
- Cetirizine is particularly effective against pruritus but may cause more sedation than other options 3
Prevention Strategies
- Have known insect nests removed by professionals 1
- Avoid wearing bright colors or flowery prints 1
- Wear protective clothing (long pants, long sleeves, closed shoes) 1
- Patients with history of systemic reactions should:
- Carry autoinjectable epinephrine
- Be educated on proper use
- Be referred to an allergist-immunologist 1
Common Pitfalls to Avoid
- Delaying removal of stingers (should be removed immediately regardless of method) 1
- Using antihistamines alone for systemic reactions instead of epinephrine 1
- Neglecting to monitor for delayed reactions, which can occur hours after the initial bite 1
- Unnecessary use of antibiotics for uncomplicated bites without signs of infection 1