From the Research
The ICD-10 code for lupus nephritis is M32.14, which specifically denotes systemic lupus erythematosus with organ or system involvement, affecting the kidneys. This code should be used when documenting lupus nephritis in medical records and for billing purposes. Lupus nephritis is a serious complication of systemic lupus erythematosus (SLE) where the immune system attacks the kidneys, causing inflammation and potentially leading to kidney damage or failure. When using this code, it's essential to also document the specific class of lupus nephritis (Class I through VI) based on renal biopsy findings if available, as this affects treatment decisions. The classification is determined by the International Society of Nephrology/Renal Pathology Society (ISN/RPS) criteria, which helps guide appropriate therapy ranging from immunosuppressants like mycophenolate mofetil or cyclophosphamide to corticosteroids depending on disease severity 1.
Some key points to consider in the management of lupus nephritis include:
- The importance of early and accurate diagnosis to improve outcomes in patients with SLE 1
- The use of immunosuppressive therapy, such as mycophenolate mofetil or cyclophosphamide, in combination with glucocorticoids 2, 3
- The potential benefits and harms of different treatment regimens, including the risk of renal relapse/flare, amenorrhea/ovarian failure, and cytopenia 4
- The distinct clinical presentation, histologic features, and natural history of membranous lupus nephritis (MLN), a subtype of lupus nephritis 5
Overall, the management of lupus nephritis requires a comprehensive approach that takes into account the individual patient's disease severity, treatment response, and potential risks and benefits of different therapies.