What are the discharge instructions for a patient with colitis?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 17, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Discharge Instructions for Colitis

For patients with colitis, the most effective discharge plan includes oral mesalamine 2-4g daily combined with topical mesalamine 1g daily in a formulation appropriate for disease extent, with continued monitoring for symptom recurrence and medication adherence. 1, 2

Medication Instructions

Primary Treatment

  • Oral mesalamine (5-ASA):
    • Take 2-4g once daily with food
    • Swallow tablets whole; do not split or crush
    • Continue taking even when feeling better
    • For maintenance: 2.4g (two 1.2g tablets) daily 1, 3

Topical Treatment (Based on Disease Extent)

  • For proctitis (rectal inflammation only):
    • Mesalamine suppositories 1g daily 1, 2
  • For proctosigmoiditis or left-sided colitis:
    • Mesalamine enemas 1g daily 1, 2

Follow-Up Care

Monitoring

  • Schedule follow-up appointment in 2-4 weeks
  • Contact healthcare provider if symptoms worsen before next appointment
  • Laboratory tests needed at follow-up:
    • Complete blood count
    • Kidney function tests
    • Liver function tests 2

Warning Signs (Call Your Doctor Immediately)

  • Severe abdominal pain
  • High fever (>38°C/100.4°F)
  • Increased bloody diarrhea
  • Inability to keep medications down
  • Signs of dehydration (dizziness, decreased urination)
  • New or worsening joint pain 1, 2

Lifestyle Modifications

Diet

  • Drink adequate fluids (at least 8-10 glasses of water daily)
  • Avoid foods that worsen symptoms (keep food diary to identify triggers)
  • Consider small, frequent meals rather than large meals
  • Limit caffeine, alcohol, and spicy foods during flares

Activity

  • Resume normal activities gradually as tolerated
  • Moderate exercise is beneficial when symptoms are controlled
  • Rest appropriately during symptom flares

Disease Management

Medication Adherence

  • Take medications as prescribed even when feeling well
  • Medication adherence is more important than higher dosing for preventing flares 4
  • Do not stop medications without consulting your doctor

Symptom Tracking

  • Keep a symptom diary noting:
    • Number of bowel movements
    • Presence of blood in stool
    • Abdominal pain (scale 1-10)
    • Factors that seem to trigger symptoms

Special Considerations

For Microscopic Colitis

  • If diagnosed with microscopic colitis, budesonide is the preferred treatment over mesalamine 1
  • Standard dosage: 9mg daily for induction of remission
  • Maintenance dosage: 6mg daily for those with symptom recurrence 1

For Severe Disease

  • If previously hospitalized for severe colitis, be vigilant for early signs of relapse
  • Follow any additional instructions for thromboprophylaxis if prescribed 1
  • Continue any prescribed immunomodulators (azathioprine or mercaptopurine) without interruption 2

Preventive Care

Vaccination

  • Stay current with vaccinations, especially if on immunosuppressive therapy
  • Annual influenza vaccination recommended
  • Pneumococcal vaccination may be recommended

Cancer Surveillance

  • Follow recommended schedule for colonoscopy surveillance
  • Typically begins 8 years after diagnosis 2

Additional Resources

  • Patient support groups: Crohn's and Colitis Foundation
  • Educational materials about inflammatory bowel disease
  • Medication assistance programs if needed for prescription costs

Remember that consistent medication use is crucial for maintaining remission, even when you feel well. Most relapses occur due to medication non-adherence rather than medication failure.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Treatment of Ulcerative Colitis

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.