From the Research
The recommended frequency and number of NAD+ infusions vary based on individual health goals and conditions, but a typical initial protocol involves 1-3 infusions per week for 2-4 weeks, followed by maintenance infusions every 1-3 months, as supported by the most recent study 1.
Key Considerations
- For general wellness and anti-aging benefits, starting with 250-500mg NAD+ per infusion is common, while therapeutic protocols for conditions like addiction recovery or neurological issues may use higher doses of 500-1000mg 1.
- Each infusion typically takes 2-4 hours to administer, as NAD+ must be infused slowly to avoid uncomfortable side effects like chest tightness or nausea.
- The rationale behind NAD+ therapy is to replenish declining NAD+ levels that occur with aging and certain health conditions, as NAD+ plays crucial roles in energy metabolism, DNA repair, and cellular signaling pathways 2, 3.
Personalization of Protocol
- Your specific protocol should be personalized by a healthcare provider based on your health status, age, and treatment goals.
- Results vary, with some people experiencing immediate benefits while others may need several sessions before noticing improvements.
Safety and Efficacy
- Supplementation with NAD+ precursors is safe, tolerable, and can increase the abundance of NAD+ and related metabolites in multiple tissues 2, 1.
- The most common side effects associated with NAD+ use are muscle pain, nervous disorders, fatigue, sleep disturbance, and headaches, but these are generally not serious 1.