When is a skull x-ray (radiograph) indicated in infants?

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Last updated: September 21, 2025View editorial policy

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Indications for Skull X-rays in Infants

Skull x-rays should not be routinely used in infants and should be limited to cases where there is visible evidence of head injury or suspicion of non-accidental trauma. 1, 2

Clinical Decision-Making Algorithm

Skull X-rays ARE indicated in infants when:

  • Suspected non-accidental trauma (child abuse) 1, 2, 3
  • Visible signs of head injury (e.g., scalp hematoma) with unclear mechanism 1, 2, 3
  • Clinical examination is equivocal and imaging is needed to rule out craniosynostosis 1
  • Suspected depressed skull fracture or penetrating injury that requires confirmation 2, 4

Skull X-rays are NOT indicated in infants when:

  • Routine screening for intracranial injury (ICI) 1, 2
  • Diagnosis of mild traumatic brain injury (mTBI) 1
  • Neurological signs/symptoms are present (CT is preferred) 1, 2
  • Routine evaluation after minor head trauma without visible injury 3, 5

Rationale and Evidence

Limited Diagnostic Value

  • Skull radiographs have only 63% sensitivity for diagnosing skull fractures in children 1
  • They cannot detect intracranial injuries such as hemorrhage, midline shift, or edema 1
  • Severe intracranial injury can occur in the absence of skull fracture 4

Preferred Imaging Alternatives

  • CT is the gold standard for detecting both skull fractures and intracranial injuries when imaging is clinically indicated 1, 2
  • MRI may provide additional diagnostic information in about 25% of children compared to CT, but is not recommended for routine acute evaluation 1, 2

Radiation Exposure Considerations

  • Reducing unnecessary skull x-rays decreases radiation exposure to infants 3, 5
  • One study demonstrated a 47.5% reduction in skull radiographs after policy change without missing significant injuries 3

Special Considerations for Infants

Anatomical Vulnerability

  • Infants have thinner skull bones, open fontanelles, larger head-to-body ratio, and weaker neck muscles 2
  • These factors make them more susceptible to head injury and require careful assessment

Clinical Assessment Challenges

  • Infants are difficult to assess clinically, which historically led to overreliance on radiological examination 3
  • Clinical neurological abnormalities are more reliable predictors of intracranial injury than skull x-rays 4

Common Pitfalls to Avoid

  1. Over-reliance on normal skull x-rays: A normal skull x-ray does not exclude intracranial injury 5, 4
  2. Missed fractures: Emergency department staff may miss up to 23% of fractures on skull radiographs 4
  3. Failure to consider non-accidental trauma: Always consider this possibility when mechanism of injury is unclear or inconsistent with injury pattern 2, 3
  4. Unnecessary radiation: Routine skull x-rays after minor head trauma expose infants to unnecessary radiation without clinical benefit 5

By following these evidence-based guidelines, clinicians can make appropriate decisions about when to use skull x-rays in infants, balancing the need for diagnostic information with concerns about radiation exposure and the limitations of this imaging modality.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Pediatric Skull Fracture and Subarachnoid Hemorrhage

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Imaging infants with head injury: effect of a change in policy.

Emergency medicine journal : EMJ, 2005

Research

[Selective indications of skull radiography after head injury in children].

Revue de chirurgie orthopedique et reparatrice de l'appareil moteur, 1996

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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