Pharyngeal Infections Cause Oropharyngeal Dysphagia
Pharyngeal infections primarily cause oropharyngeal dysphagia, characterized by difficulty initiating swallowing and transferring food from the mouth to the esophagus. 1, 2
Understanding Oropharyngeal Dysphagia
Oropharyngeal dysphagia occurs when there are problems with:
- Forming a cohesive bolus
- Transferring food from the mouth into the pharynx
- Initiating the involuntary swallowing process 2
Patients with oropharyngeal dysphagia typically present with:
- Food sticking in the throat
- Globus sensation (feeling of a lump in the throat)
- Coughing or choking during swallowing
- Nasal-quality voice or nasal regurgitation
- Food dribbling from the mouth
- Difficulty initiating swallow 1
Pathophysiology of Infection-Related Dysphagia
When pharyngeal infections occur, they can cause:
- Inflammation of pharyngeal muscles
- Pain during swallowing (odynophagia) which often accompanies dysphagia
- Impaired contraction of pharyngeal muscles
- Reduced hyolaryngeal excursion 3
Diagnostic Approach
For patients with suspected pharyngeal infection causing dysphagia, the American College of Radiology recommends:
- Videofluoroscopic Swallowing Study (VFSS): Gold standard for evaluating swallowing dynamics 4
- Fiberoptic Endoscopic Evaluation of Swallowing (FEES): To visualize pharyngeal and laryngeal anatomy during swallowing 4
- Biphasic Esophagram: Initial diagnostic test for unexplained dysphagia, allowing comprehensive evaluation of both the pharynx and esophagus 1, 4
Screening tools that can be helpful include:
- EAT-10 questionnaire (sensitivity 86%, specificity 76%)
- Volume-Viscosity Test (V-VST) (sensitivity 92%, specificity 80%) 4
Clinical Implications and Management
Management of pharyngeal infection-induced dysphagia should focus on:
Treating the underlying infection:
- Appropriate antimicrobial therapy based on the causative organism
- Antifungal agents for candidiasis
- Antiviral agents for viral infections 5
Addressing swallowing difficulties:
- Postural changes (chin down or head turn) to improve airway protection
- Dietary modifications using the International Dysphagia Diet Standardisation Initiative (IDDSI) framework
- Thickened liquids for patients with aspiration risk 4
Multidisciplinary care:
- Speech-Language Pathologist (SLP) for swallowing therapy
- Dietician for nutritional management
- Physician for medical management of infection 4
Important Considerations and Pitfalls
- Silent aspiration: Up to 55% of patients who aspirate may not exhibit protective cough reflexes, increasing pneumonia risk 4
- Dehydration risk: When using thickened liquids, monitor hydration status carefully 4
- Residual symptoms: Dysphagia may persist even after the infection resolves due to muscle weakness or scarring 3
- Referred symptoms: Abnormalities of the mid or distal esophagus may cause referred dysphagia to the upper chest or pharynx 1
Remember that pharyngeal infections represent a treatable cause of oropharyngeal dysphagia, and prompt identification and management can significantly improve outcomes and prevent complications like aspiration pneumonia.