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Differential Diagnosis for Right Hypochondriac Pain

Single Most Likely Diagnosis

  • Gallbladder Disease: The most common cause of right hypochondriac pain is gallbladder disease, including cholecystitis or cholelithiasis. The pain is often sharp and may radiate to the right shoulder.

Other Likely Diagnoses

  • Peptic Ulcer Disease: Peptic ulcers can cause pain in the right hypochondriac region, especially if the ulcer is located in the duodenum.
  • Hepatitis: Inflammation of the liver can cause right hypochondriac pain, and it may be accompanied by jaundice and other systemic symptoms.
  • Right Lower Lobe Pneumonia: Pneumonia affecting the right lower lobe of the lung can cause referred pain to the right hypochondriac region.
  • Intercostal Muscle Strain: Strain of the intercostal muscles can cause pain in the right hypochondriac region, especially if the strain occurs in the muscles between the 6th to 9th ribs.

Do Not Miss Diagnoses

  • Myocardial Infarction: Although less common, myocardial infarction can present with pain in the right hypochondriac region, especially if the inferior wall of the heart is involved.
  • Pulmonary Embolism: A pulmonary embolism can cause sudden onset of right hypochondriac pain, especially if the embolism is located in the right lower lobe.
  • Hepatic Abscess: A hepatic abscess can cause severe right hypochondriac pain and is a medical emergency.
  • Cholangitis: Inflammation of the bile ducts can cause severe right hypochondriac pain and is a medical emergency.

Rare Diagnoses

  • Hepatocellular Carcinoma: A rare cause of right hypochondriac pain, hepatocellular carcinoma can cause pain in the right upper quadrant.
  • Right Diaphragmatic Hernia: A rare condition where the diaphragm is herniated, causing abdominal contents to protrude into the thoracic cavity, can cause right hypochondriac pain.
  • Intrahepatic Duct Stones: Stones in the intrahepatic ducts can cause recurrent right hypochondriac pain.
  • Sickle Cell Disease: Sickle cell disease can cause episodes of right hypochondriac pain due to sickling of red blood cells in the liver and spleen.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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