Step-by-Step Intubation Procedure
Intubation must be approached as a carefully planned procedure with preparation for potential complications, as all patients in intensive care units should be considered at risk of complicated intubation. 1
Pre-Intubation Assessment
Airway Assessment
- Evaluate for difficult airway risk factors using the MACOCHA score (score ≥3 predicts difficult intubation) 2
- Assess airway anatomy:
- Mallampati classification
- Neck mobility
- Mouth opening
- Identify cricothyroid membrane using "laryngeal handshake" technique
- Consider body habitus (BMI >30 increases risk 2×, BMI >40 increases risk 4×) 2
Physiological Assessment
- Evaluate cardiorespiratory status
- Optimize hemodynamics before proceeding
- Identify patients who cannot safely tolerate hypoxemia (epilepsy, cerebrovascular disease, coronary artery disease) 1
Equipment Preparation
- Assemble and check all equipment:
- Laryngoscope (Macintosh blade preferred for first attempt)
- Appropriately sized endotracheal tube
- Stylet/bougie
- Suction equipment
- Bag-valve-mask with oxygen source
- End-tidal CO2 detector
- Backup devices (video laryngoscope, supraglottic airway)
- Assign clear roles to team members 2
- Discuss backup plans (Plan A, B, C, D) for failed intubation 2
Patient Positioning
- Position patient with head elevated 25-30° when tolerated 2
- Use firm bed mattress for optimal cricoid pressure application if needed 2
- Consider "sniffing position" (neck flexion, head extension) for optimal glottic visualization
Pre-Oxygenation
- Pre-oxygenate with 100% oxygen for 3-5 minutes
- Aim for SpO2 >95% before proceeding
- Consider non-invasive ventilation or high-flow nasal oxygen for patients with respiratory failure
Medication Administration
- Administer appropriate medications in sequence:
- Premedication (if indicated)
- Induction agent
- Neuromuscular blocking agent (rocuronium 0.6 mg/kg is standard dose) 3
- For rapid sequence intubation, rocuronium 0.6-1.2 mg/kg provides excellent intubating conditions in most patients within 2 minutes 3
Intubation Procedure
- Wait for adequate muscle relaxation (typically 45-60 seconds with rocuronium) 3
- Hold laryngoscope in left hand
- Insert laryngoscope into right side of mouth
- Sweep tongue to left
- Advance blade to vallecula (Macintosh) or posterior to epiglottis (Miller)
- Lift laryngoscope forward and upward (avoid levering)
- Apply external laryngeal manipulation if needed (BURP maneuver)
- Visualize vocal cords
- Insert endotracheal tube through vocal cords with right hand
- Advance tube until cuff disappears past vocal cords
- Hold tube firmly while removing laryngoscope
- Inflate cuff with minimum air needed to seal airway
Confirmation of Placement
- Check for bilateral chest rise
- Auscultate bilateral breath sounds and over epigastrium
- Confirm with end-tidal CO2 detection (most reliable method)
- Secure tube properly
- Obtain chest X-ray for confirmation of position
Post-Intubation Management
- Initiate post-intubation sedation promptly (within 15 minutes) 2
- Verify ventilation, oxygenation, and cardiovascular stability
- Document procedure details, including:
- Laryngoscopic view obtained
- Number of attempts
- Complications encountered
- Tube size and depth
Common Pitfalls to Avoid
- Delayed recognition of respiratory failure
- Inadequate preparation for difficult airway
- Multiple intubation attempts without changing approach
- Failure to call for help early
- Proceeding despite borderline respiratory status 2
- Using succinylcholine in patients with neuromuscular disorders 2
Management of Complications
- Severe hypoxemia: Immediately ventilate with bag-mask and 100% oxygen
- Hypotension: Administer fluid bolus and/or vasopressors
- Failed intubation: Follow difficult airway algorithm, consider supraglottic airway device (maximum two insertion attempts) 2
- Front-of-neck access if oxygenation cannot be maintained (surgical technique preferred over needle cricothyroidotomy) 2
By following this systematic approach to intubation, clinicians can minimize the risk of complications and improve patient outcomes in this critical procedure.