What methods reduce the risk of healthcare-associated infections to achieve a high asepsis score?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: September 27, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Methods to Reduce Healthcare-Associated Infections for High Asepsis Score

Hand hygiene and proper use of personal protective equipment are the most fundamental and effective methods to reduce healthcare-associated infections and achieve a high asepsis score. 1

Hand Hygiene

  • Decontaminate hands by washing with antimicrobial soap and water or using alcohol-based waterless antiseptic agents when hands are not visibly soiled 1
  • Perform hand hygiene before and after contact with patients, especially those with invasive devices 1
  • Perform hand hygiene after handling respiratory secretions or objects contaminated with secretions 1
  • Decontaminate hands between contacts with different patients and between contacts with a contaminated body site and the respiratory tract 1

Personal Protective Equipment (PPE)

  • Wear gloves when handling respiratory secretions or objects contaminated with respiratory secretions 1
  • Change gloves between contacts with different patients 1
  • Change gloves after handling respiratory secretions before contact with another patient, object, or environmental surface 1
  • Wear gowns when soiling with respiratory secretions is anticipated 1
  • Change gowns after soiling occurs and before providing care to another patient 1

Aseptic Technique for Procedures

  • Perform invasive procedures (e.g., tracheostomy) under strict aseptic conditions 1
  • When changing tracheostomy tubes:
    • Wear a gown
    • Use aseptic technique
    • Replace the tube with one that has undergone sterilization or high-level disinfection 1
  • For suctioning of respiratory tract secretions:
    • Use sterile, single-use catheters if using open-system suction 1
    • Use only sterile fluid to remove secretions from suction catheters if they will re-enter the patient's lower respiratory tract 1

Equipment Sterilization and Disinfection

  • Change the mouthpiece of peak flow meters or the mouthpiece and filter of spirometers between uses on different patients 1
  • Avoid using large-volume room-air humidifiers that create aerosols unless they can be sterilized or subjected to high-level disinfection daily 1
  • Use only sterile water in humidifiers 1
  • Apply chlorhexidine gluconate for oral decontamination to reduce the risk of ventilator-associated pneumonia 2, 3

Environmental Controls

  • Maintain a clean surgical environment 4
  • Remove faucet aerators in units where immunocompromised patients are treated if Legionella species are detected 1
  • Implement selective oral decontamination and selective digestive decontamination to reduce ventilator-associated pneumonia 1

Nursing Interventions

  • Practice and promote hand hygiene consistently 1
  • Use standard precautions consistently 1
  • Ensure proper cleaning and disinfection practices 1
  • Remove unnecessary invasive devices promptly 1
  • Implement bundle strategies for infection prevention 1
  • Place patients in semi-recumbent position (head of bed elevated 30-45°) to prevent ventilator-associated pneumonia 2

Antibiotic Stewardship

  • Avoid prolonging antibiotic prophylaxis after surgery, as it is generally not associated with better clinical outcomes 1
  • De-escalate to the most appropriate single therapy as soon as the susceptibility profile is known 1
  • Administer effective intravenous antibiotics within the first hour of sepsis recognition 2

Patient Education

  • Implement educational and training interventions concerning the prevention of surgical site infections 1
  • Ensure patients are effectively educated throughout their hospitalization to prepare them for self-care 1

Common Pitfalls and Caveats

  • Failure to change gloves between patients is a common breach of aseptic technique 5
  • Confusion between "clean," "aseptic," or "sterile" technique can lead to improper practices, especially in home healthcare settings 6
  • Lack of competency-based training that doesn't reflect the critical importance of aseptic technique to patient safety 6
  • Failure to recognize when aseptic technique has been breached and not taking immediate corrective action 7
  • Underestimating the importance of proper hand hygiene as the most fundamental infection prevention measure 1

By implementing these evidence-based practices systematically, healthcare facilities can significantly reduce healthcare-associated infections and achieve high asepsis scores, ultimately improving patient outcomes and reducing morbidity and mortality.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Sepsis with Pulmonary Focus

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

[Aseptic techniques for minor surgical procedures].

Revista medica de Chile, 2016

Research

Asepsis: a prophylactic technique.

Seminars in perioperative nursing, 1994

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.