What is the diagnosis and treatment for a Lisfranc (midfoot) fracture?

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Diagnosis and Treatment of Lisfranc (Midfoot) Fractures

Lisfranc injuries require standard radiographs as first-line imaging, followed by CT and/or MRI for definitive diagnosis, with treatment determined by stability - stable injuries can be managed conservatively while unstable injuries require surgical fixation to prevent long-term disability. 1

Diagnosis

Clinical Assessment

  • Look for midfoot swelling, pain, and plantar ecchymosis (highly characteristic sign) 2
  • Specific clinical tests:
    • Apply dorsomedial to plantar-lateral force across the 1st metatarsal base (positive test indicates hypermobility) 1
    • Evaluate sagittal plane motion (>4 degrees indicates hypermobility) 1
    • Assess transverse plane motion (>8 degrees indicates hypermobility) 1

Imaging Protocol

  1. Initial Imaging: Three-view radiographic study (anteroposterior, oblique, lateral) 3, 1

    • Add AP view with 20° craniocaudal angulation for suspected Lisfranc injury 3
    • Weight-bearing radiographs are crucial as they increase visibility of abnormal alignment 3, 1
    • Include both feet on AP radiographs to compare with uninjured side 3
  2. Advanced Imaging:

    • CT scan: Essential for detecting non-displaced fractures (25% of midfoot fractures are missed on radiographs) 1

      • Weightbearing CT provides functional assessment of instability under physiologic load 1
      • Particularly important for preoperative planning and polytrauma cases 3, 1
    • MRI: Gold standard for ligamentous injuries 1, 2

      • Most sensitive for occult fractures and bone stress changes 1
      • Indicated when radiographs are normal but clinical suspicion remains high 1

Caution: Up to 20% of Lisfranc injuries are initially missed or diagnosed late, especially low-energy trauma that may be mistaken for simple midfoot sprains 2, 4

Treatment

Classification-Based Management

Treatment depends on stability and displacement:

  1. Stable, Undisplaced Injuries (Stage I):

    • Conservative management 2, 5
    • Non-weightbearing immobilization for 6 weeks 1, 2
    • Immobilization options (in order of preference):
      • Non-removable knee-high total contact cast (first-line) 1
      • Pre-fabricated knee-high walker (second-line) 1
      • Removable knee-high device (third-line) 1
  2. Unstable or Displaced Injuries (Stage II/III):

    • Surgical intervention required 1, 2, 4
    • Surgical options:
      • Open reduction and internal fixation (ORIF) with transarticular screws 1, 4
      • Dorsal plate fixation (preferred for comminuted fractures) 4
      • Primary arthrodesis in certain cases 4
      • Percutaneous screw fixation (minimally invasive option) 1

Post-Treatment Protocol

  • Non-weightbearing for 6 weeks post-treatment 1
  • Partial progressive weightbearing with arch support from weeks 6-12 1
  • Full weightbearing and return to activity at 12-16 weeks 1
  • Long-term use of appropriate footwear and orthoses 1

Potential Complications

  • Post-traumatic osteoarthritis (occurs in up to 45% of cases despite appropriate treatment) 1, 2
  • Chronic pain and foot deformities 2, 4
  • Hardware failure and loss of reduction 1

Key to Success: Anatomical reduction is the major determinant of good long-term outcomes 1, 4. Early detection and appropriate management are essential to prevent progression to arthritis and long-term disability 1.

Follow-up

  • Regular clinical and radiographic follow-up to ensure proper alignment and healing 1
  • Long-term monitoring for development of post-traumatic arthritis 1
  • Functional rehabilitation once healing permits 1

References

Guideline

Assessment and Management of Foot Instability

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Lisfranc complex injuries management and treatment: current knowledge.

International journal of physiology, pathophysiology and pharmacology, 2022

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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