How do you interpret a foot/ankle X-ray for Lisfranc (injury of the joints in the middle of the foot), ankle fracture, and Jones (fracture at the base of the fifth metatarsal)/pseudo-Jones (avulsion fracture at the base of the fifth metatarsal) fractures, including relevant negatives?

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Systematic Approach to Foot/Ankle X-ray Interpretation

Initial Imaging Protocol

Always obtain weight-bearing radiographs as your first-line study, as non-weight-bearing films are unreliable for detecting subtle injuries, particularly Lisfranc injuries. 1, 2, 3

Standard Views Required

  • Three-view series: anteroposterior (AP), oblique, and lateral projections 1
  • Additional AP view with 20° craniocaudal angulation to improve visualization of the Lisfranc joint complex 1, 2
  • Bilateral imaging with both feet on AP radiographs to detect subtle malalignment by comparing to the uninjured side 1, 2, 3

Lisfranc Injury Interpretation

Positive Radiographic Findings

  • Diastasis between the first and second metatarsal bases (>2mm widening) 1, 4
  • "Fleck" sign: small avulsion fracture fragment between the base of the first and second metatarsals, representing avulsion of the Lisfranc ligament 1, 4
  • Loss of alignment between the medial border of the second metatarsal base and medial border of the middle cuneiform on AP view 4
  • Loss of alignment between the medial border of the fourth metatarsal and medial border of the cuboid on oblique view 4
  • Associated metatarsal and cuneiform fractures 5

Critical Relevant Negatives

  • Normal alignment of the medial border of the second metatarsal base with the middle cuneiform 4
  • No diastasis between first and second metatarsal bases (<2mm spacing) 1
  • Absence of fleck sign 1, 4
  • Intact Lisfranc joint space on all three views 1

When to Advance Beyond X-ray

If radiographs are normal but clinical suspicion remains high (midfoot swelling, plantar ecchymosis, inability to bear weight), you must obtain advanced imaging—do not stop at negative X-rays. 1, 3

  • CT is your primary advanced imaging for acute hyperflexion injuries, high-energy trauma, polytrauma patients, or those unable to bear weight 5, 1, 3
  • CT detects 25% of midfoot fractures missed on radiographs in polytrauma patients 1, 3
  • MRI is indicated when radiographs are normal but you suspect purely ligamentous injury without diastasis 1, 2, 3
  • MRI with 3-D volumetric acquisitions shows high correlation with intraoperative findings for unstable Lisfranc injuries 5, 1, 3

Ankle Fracture Interpretation

Positive Radiographic Findings

  • Fracture lines involving the medial malleolus, lateral malleolus, or posterior malleolus 6
  • Widening of the mortise (>4mm medial clear space or asymmetric tibiofibular clear space) indicating syndesmotic injury 6
  • Talar shift or subluxation within the ankle mortise 6
  • Associated fibular fracture location (helps classify injury pattern per Lauge-Hansen) 6

Critical Relevant Negatives

  • Intact medial clear space (should be ≤4mm and symmetric with superior clear space) 6
  • Normal tibiofibular overlap on AP view (≥6mm) and mortise view (≥1mm) 6
  • Concentric talar position within the mortise on all views 6
  • No cortical disruption of malleoli or tibial plafond 6

Classification Approach

Use three views (AP, mortise, lateral) to identify the position of the foot at injury and direction of deforming force per Lauge-Hansen classification. 6


Jones vs Pseudo-Jones Fracture Interpretation

Jones Fracture (True Jones)

  • Transverse fracture at the metaphyseal-diaphyseal junction of the fifth metatarsal, 1.5-3cm distal to the tuberosity 3
  • Fracture line extends into the intermetatarsal articulation between the fourth and fifth metatarsals
  • No extension into the tarsometatarsal joint

Pseudo-Jones (Avulsion Fracture)

  • Avulsion fracture at the base of the fifth metatarsal tuberosity (proximal to Jones fracture location)
  • Fracture line oriented transversely or obliquely through the tuberosity
  • May extend into the fifth metatarsal-cuboid joint
  • Caused by peroneus brevis tendon avulsion

Critical Relevant Negatives

  • No cortical disruption at the base of the fifth metatarsal 3
  • Normal soft tissue contour without swelling over lateral midfoot
  • Intact fifth metatarsal-cuboid articulation

Critical Pitfalls to Avoid

Most Common Diagnostic Errors

  • Never rely solely on non-weight-bearing radiographs for suspected Lisfranc injuries—this is the leading cause of missed diagnoses 1, 2, 3
  • Up to 20% of Lisfranc injuries are missed or diagnosed late, especially low-energy purely ligamentous injuries 7, 8
  • In diabetic patients with neuropathy, standard clinical tests are unreliable and patients may bear weight despite fractures—image more liberally 2, 3
  • Radiographs have only 25-33% sensitivity for midfoot fractures in Level 1 trauma patients 5

When Initial X-rays Are Negative

Do not stop at negative radiographs if clinical suspicion is high—conventional radiographs including weight-bearing images are insufficient for acute hyperflexion injuries. 5, 3

  • Proceed to CT for high-energy mechanisms, polytrauma, or inability to bear weight 5, 1, 3
  • Proceed to MRI for suspected soft tissue injuries, ligamentous Lisfranc injuries, or occult fractures in athletes 5, 3
  • CT reveals additional occult fractures in 46% of cases with positive radiographs and 35% of cases in other parts of the foot/ankle 9

References

Guideline

Diagnostic Criteria for Lisfranc Fracture of the Foot

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Diagnostic Approach and Management of Tarsometatarsal Joint Injuries

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Imaging Guidelines for Foot Trauma

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Lisfranc complex injuries management and treatment: current knowledge.

International journal of physiology, pathophysiology and pharmacology, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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