Are treatments for intertrigo available over the counter?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 1, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Over-the-Counter Treatment Options for Intertrigo

Yes, several effective treatments for intertrigo are available over the counter, including antifungal creams, barrier preparations, and moisture-absorbing powders that can address both the primary condition and common secondary infections.

Understanding Intertrigo

Intertrigo is an inflammatory skin condition that occurs in skin folds where surfaces rub against each other, creating friction, moisture, and lack of ventilation. Common locations include:

  • Under breasts
  • Abdominal folds
  • Groin and inner thighs
  • Axillae (armpits)
  • Between toes

Available OTC Treatment Options

Antifungal Treatments

  • Clotrimazole 1% cream: Applied twice daily for 2-4 weeks 1
  • Miconazole: Available as cream or powder, applied twice daily
  • Terbinafine 1% cream: Applied daily for 1-2 weeks 1
  • Butenafine: For adults with fungal infections 1
  • Oxiconazole: Effective for candidal intertrigo 2
  • Econazole: Useful for fungal components of intertrigo 2

Moisture Control Products

  • Cornstarch-based powders: Help absorb moisture and reduce friction 3
  • Zinc oxide creams: Create a protective barrier against moisture and irritants
  • Talc-free absorbent powders: Reduce moisture in skin folds

For Secondary Bacterial Infections

  • Antiseptic washes: Containing chlorhexidine or povidone-iodine
  • Antibacterial soaps: Help control bacterial overgrowth

Treatment Approach

  1. First step: Clean and thoroughly dry affected areas

  2. For simple intertrigo without infection:

    • Apply barrier preparations (zinc oxide)
    • Use moisture-absorbing powders (cornstarch)
    • Wear light, non-constricting, absorbent clothing 3
  3. For intertrigo with fungal infection (signs: satellite pustules, scaling edges):

    • Apply OTC antifungal creams like clotrimazole or miconazole twice daily 2
    • Continue treatment for 1-2 weeks after visible improvement
  4. For persistent cases:

    • Consider combination products containing mild corticosteroids with antifungals
    • If no improvement after 2 weeks, seek medical attention as prescription treatments may be needed 4

Prevention Strategies

  • Keep skin folds clean and dry
  • Use moisture-wicking fabrics between skin folds 4
  • Wear open-toed shoes for toe web intertrigo 3
  • Shower after exercise and thoroughly dry skin fold areas
  • Avoid tight clothing, especially in hot, humid weather

Important Caveats

  • If symptoms worsen or don't improve within 2 weeks, consult a healthcare provider
  • Diabetic patients should seek medical attention sooner due to increased risk of complications
  • Extensive, painful, or rapidly spreading rashes require prompt medical evaluation
  • OTC treatments are most effective for mild to moderate cases; severe cases may require prescription medications 5

Remember that proper skin fold hygiene and keeping the affected areas dry are as important as the topical treatments themselves in managing intertrigo.

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Intertrigo and secondary skin infections.

American family physician, 2014

Research

Intertrigo and common secondary skin infections.

American family physician, 2005

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.