What are the steps to interpret an electrocardiogram (ECG)?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: October 3, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

Systematic Approach to ECG Interpretation

A systematic approach to ECG interpretation should follow specific steps that assess rate, rhythm, intervals, axis, hypertrophy, and ischemic changes to ensure accurate diagnosis and appropriate clinical management. 1

Step 1: Assess Heart Rate and Rhythm

  • Calculate heart rate by counting the number of QRS complexes in a 6-second strip and multiplying by 10, or using the formula 300 divided by the number of large boxes between consecutive R waves 1
  • Identify the underlying rhythm by confirming if there is a P wave before each QRS complex with consistent PR interval (sinus rhythm) 1
  • Note if the rate is normal (60-100 bpm), bradycardic (<60 bpm), or tachycardic (>100 bpm) 1
  • Assess rhythm regularity, noting any premature beats, pauses, or completely irregular patterns that might suggest atrial fibrillation 1

Step 2: Evaluate Intervals and Conduction

  • Measure the PR interval (normal: 120-200 ms) to assess AV conduction 1
  • Evaluate QRS duration (normal: <120 ms) to identify ventricular conduction delays 1
  • Calculate the QT interval corrected for heart rate (QTc) using Bazett's formula (normal: <450 ms for men, <460 ms for women) 1
  • Identify any conduction abnormalities such as AV blocks, bundle branch blocks, or pre-excitation 1

Step 3: Determine Electrical Axis

  • Examine leads I and aVF to determine the electrical axis 1
  • Normal axis: +90° to -30° (positive in both leads I and aVF) 1
  • Left axis deviation: -30° to -90° (positive in lead I, negative in aVF) 1
  • Right axis deviation: +90° to +180° (negative in lead I, positive in aVF) 1
  • Extreme axis deviation: +180° to -90° (negative in both leads I and aVF) 1

Step 4: Assess Chamber Enlargement

  • Look for voltage criteria for left ventricular hypertrophy: S in V1 + R in V5 or V6 >3.5 mV 1
  • Assess for atrial enlargement patterns 1
  • Consider other hypertrophy patterns that may suggest specific cardiomyopathies 2

Step 5: Evaluate for Ischemia, Injury, and Infarction

  • Examine for ST-segment deviations (ST elevation >0.1 mV in limb leads or >0.15-0.2 mV in precordial leads may indicate acute injury) 1
  • Look for T-wave abnormalities (inversion, hyperacute, flattening) 1
  • Identify pathological Q waves (>0.04 seconds or >25% of the R wave amplitude) suggesting myocardial infarction 1
  • Note the location of abnormalities to determine the affected coronary territory 1

Important Considerations

  • Compare with previous ECGs when available to identify significant changes 1
  • Consider the clinical context when interpreting findings 3
  • Be aware that computer interpretation should be considered a helpful adjunct but not a substitute for physician interpretation 4
  • Remember that certain populations may have normal variants (e.g., athletes commonly have sinus bradycardia) 1

Common Pitfalls to Avoid

  • Electrode misplacement, particularly precordial leads, which can significantly alter ECG interpretation 1
  • Inadequate filtering settings that can distort waveforms and affect measurements 1
  • Over-reliance on computer interpretation without physician verification 4, 1
  • Failure to compare with previous ECGs when available 1
  • Interpreting ECG findings in isolation without considering clinical context 1, 3

By following this systematic approach, clinicians can ensure thorough and accurate interpretation of ECGs, leading to appropriate clinical decision-making and improved patient outcomes.

References

Guideline

EKG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

The Electrocardiogram: Still a Useful Tool in the Primary Care Office.

The Medical clinics of North America, 2019

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.