What is the treatment for mastitis?

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Treatment of Mastitis

For lactational mastitis, treatment should begin with conservative measures for 1-2 days, including continued breastfeeding, NSAIDs, and ice application, followed by antibiotics if symptoms persist. 1

Initial Management Approach

  • Mothers with mastitis should be encouraged to continue breastfeeding. Regular feeding or expression of milk is an essential part of treatment 2
  • Apply conservative measures for 1-2 days as first-line treatment 1:
    • Nonsteroidal anti-inflammatory drugs (NSAIDs) for pain and inflammation
    • Ice application to reduce inflammation
    • Feed the infant directly from the affected breast
    • Minimize excessive pumping which can worsen inflammation

When to Use Antibiotics

  • If no improvement occurs after 1-2 days of conservative measures, narrow-spectrum antibiotics should be initiated 1
  • Antibiotics should target common skin flora, particularly Staphylococcus aureus, which is a common causative organism 1, 3
  • Milk cultures should be considered to guide antibiotic therapy in cases that don't respond to initial treatment 1

Antibiotic Selection

  • Although evidence from randomized controlled trials is limited, antibiotics effective against Staphylococcus aureus are typically used 3
  • Common antibiotic choices include:
    • Dicloxacillin
    • Flucloxacillin
    • Cephalexin
    • Amoxicillin-clavulanate 1

Management of Complications

  • Approximately 10% of mastitis cases progress to breast abscesses, which require drainage 2
  • Breastfeeding can continue on the affected side as long as the infant's mouth does not contact purulent drainage from the breast 2
  • Ultrasonography should be performed to identify abscesses in immunocompromised patients or those with worsening or recurrent symptoms 1

Special Considerations

  • Most patients can be treated as outpatients with oral antibiotics 1
  • If the condition worsens or there is concern for sepsis, intravenous antibiotics and hospital admission may be required 1
  • Factors that increase the risk of mastitis include overstimulation of milk production and tissue trauma 1

Prevention Strategies

  • The best prevention is proper lactation technique, including a good infant latch 1
  • Encourage physiologic breastfeeding rather than pumping when possible 1
  • Avoid practices that may worsen the condition, such as:
    • Excessive pumping to empty the breast
    • Heat application
    • Aggressive breast massage 1

Common Pitfalls to Avoid

  • Discontinuing breastfeeding during mastitis treatment, which can actually worsen the condition 2
  • Overuse of antibiotics for mild cases that could resolve with conservative measures 1, 3
  • Excessive pumping and breast massage, which can cause tissue trauma and worsen inflammation 1
  • Delaying treatment of non-responsive cases, which may lead to abscess formation 2

References

Research

Mastitis: Rapid Evidence Review.

American family physician, 2024

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Antibiotics for mastitis in breastfeeding women.

The Cochrane database of systematic reviews, 2013

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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