From the Guidelines
Cisplatin is a commonly used cancer medicine.
Commonly Used Cancer Medicines
- Cisplatin is one of the three drug types active in the management of advanced bladder cancer, along with the taxanes and gemcitabine 1.
- Combinations of these agents, such as GC (gemcitabine and cisplatin) or MVAC (methotrexate, vinblastine, doxorubicin, and cisplatin), have shown clinical benefit in the treatment of bladder cancer 1.
- Cisplatin is also used in the treatment of other types of cancer, including ovarian cancer, and is often used in combination with other drugs such as carboplatin and paclitaxel 1.
- The use of cisplatin and other cancer medicines should be individualized based on the patient's performance status, extent of disease, and specific prior therapy administered 1.
- It is essential to consider the potential benefits and risks of cancer-directed therapy, including the possibility of adverse reactions, and to discuss these with patients and their families 1.
From the Research
Commonly Used Cancer Medicines
- Doxorubicin, also known as Adriamycin, is one of the most widely used chemotherapeutic drugs for treating various types of cancer 2
- Metformin, an anti-diabetic drug, has been reported to show potential activity against cancerous cells 3, 4
- Benzodiazepines, such as Diazepam and Midzolam, have been found to have anti-cancerous activity 3
- Antidepressants, including Imipramine, Clomipramine, and Citalopram, have shown promising anti-cancer activities 3
- Antiepileptic drugs, such as Valporic acid and Phenytoin, have been reported to have potential anti-cancer effects 3
Drug Repurposing for Cancer Treatment
- Drug repurposing has the potential to overcome the challenges faced in conventional drug discovery and is becoming an area of interest for researchers and scientists 3
- Several drugs originally approved for indications other than cancer treatment have been found to have a cytostatic effect on cancer cells and could be repurposed as anti-cancer agents 4