What is the recommended treatment for a cat bite?

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Last updated: October 13, 2025View editorial policy

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Treatment for Cat Bite

The recommended treatment for a cat bite includes immediate and thorough wound cleansing with soap and water for 15 minutes, followed by prophylactic antibiotic therapy with amoxicillin-clavulanate, assessment for rabies exposure, and tetanus prophylaxis as indicated. 1

Initial Wound Management

  • Immediately wash and flush all bite wounds thoroughly with soap and water for about 15 minutes to reduce infection risk and potential rabies transmission 2, 1
  • Apply a virucidal agent such as povidone-iodine solution for irrigation after cleaning 2
  • Thorough wound cleansing alone has been shown to markedly reduce the likelihood of rabies in animal studies 2
  • The decision to suture large wounds should consider cosmetic factors and bacterial infection potential; generally, cat bite wounds should not be sutured due to high infection risk 2, 1

Antibiotic Prophylaxis

  • Amoxicillin-clavulanate is the first-line prophylactic antibiotic for cat bite wounds 1, 3
    • Adult dosage: 875/125 mg twice per day orally 2
    • Pediatric dosage: 25 mg/kg/day of the amoxicillin component in 2 divided doses orally 2
  • Alternative options for penicillin-allergic patients include:
    • Doxycycline (not recommended for children under 8 years) 1
    • Fluoroquinolone plus an agent active against anaerobes 1
  • First-generation cephalosporins, penicillinase-resistant penicillins, macrolides, and clindamycin alone should be avoided due to poor activity against Pasteurella multocida 1

Rationale for Aggressive Treatment

  • Cat bites have a significantly higher infection rate (20-80%) compared to dog bites (3-18%) 3, 4
  • Pasteurella multocida is found in approximately 90% of domestic cats' oral cavities and is the most common pathogen in infected cat bite wounds 3
  • Cat bite wounds on the hand have the greatest risk of infection and potential for serious complications 5, 6, 7
  • Risk factors for infection include:
    • Older patient age 6
    • Longer time intervals until treatment 6
    • Deeper wounds, especially puncture wounds 6
    • Lower extremity wounds 6

Rabies Considerations

  • Assessment for potential rabies exposure is essential for all cat bites 1
  • A healthy domestic cat that bites a person may be confined and observed for 10 days 2
  • Any illness in the animal during confinement should be evaluated by a veterinarian and reported to the local public health department 2
  • If the biting cat is stray or unwanted, it should either be observed for 10 days or be euthanized immediately and submitted for rabies examination 2
  • Rabies post-exposure prophylaxis should be considered based on the circumstances of the bite and the animal's vaccination status 2

Tetanus Prophylaxis

  • Administer tetanus prophylaxis as indicated based on the patient's immunization status 2, 1
  • For patients with unknown or incomplete tetanus immunization, tetanus toxoid should be administered 1

Special Considerations

  • Hand wounds require particularly careful evaluation and treatment due to higher complication rates 1, 7
  • Wounds involving joints, tendons, ligaments, or fractures require more aggressive management 1
  • Monitor for potential complications including septic arthritis, osteomyelitis, subcutaneous abscess formation, tendonitis, and bacteremia 1
  • Pain disproportionate to the severity of injury near a bone or joint may suggest periosteal penetration 1

References

Guideline

Dog Bite Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Infectious Complications of Bite Injuries.

Infectious disease clinics of North America, 2021

Research

Management of cat and dog bites.

American family physician, 1995

Research

Cat bite wounds: risk factors for infection.

Annals of emergency medicine, 1991

Research

Cat bites of the hand.

ANZ journal of surgery, 2004

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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