What is the treatment and management protocol for an L2 vertebral compression fracture?

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Management Protocol for L2 Vertebral Compression Fracture

For L2 vertebral compression fractures, initial conservative management for 2-12 weeks is recommended for stable fractures without neurological deficits, followed by vertebral augmentation if pain persists or complications develop. 1

Initial Assessment

  • Determine fracture stability based on absence of neurological deficits, minimal height loss (<10%), absence of retropulsion, and minimal deformity (<15% kyphosis, <10% scoliosis) 2
  • MRI with fluid-sensitive sequences helps identify acute fractures, fracture clefts, and differentiate synchronous fractures 1
  • Bone scan or SPECT/CT may help determine fracture age when clinical history is unclear 1

Conservative Management (First-Line for Stable Fractures)

  • Pain control with analgesics including NSAIDs and limited use of narcotics (caution with sedation and fall risk) 1
  • Limited bed rest to avoid complications of immobility (bone density decreases ~2% per week, muscle strength decreases 1-3% per day) 1
  • Bracing for comfort and stabilization 3
  • Physical therapy to maintain strength and mobility 4
  • Osteoporosis management:
    • Calcium (1000mg daily) and vitamin D (400 IU daily) supplementation 5
    • Bisphosphonates like alendronate reduce risk of subsequent vertebral fractures by 48% 6
    • Denosumab (60mg SQ every 6 months) reduces new vertebral fractures by 68% compared to placebo 5

Indications for Vertebral Augmentation

  • Failure of conservative management with persistent pain after 3 weeks 1
  • Severe pain requiring parenteral narcotics or hospitalization 1
  • Spinal deformity or pulmonary dysfunction 1
  • Risk factors for failure of conservative treatment: age >78.5 years, severe osteoporosis (T-score <-2.95), BMI >25.5, vertebral collapse >28.5% 7

Vertebral Augmentation Techniques

  • Vertebroplasty (VP): Injection of bone cement into fractured vertebra 1
  • Balloon kyphoplasty (BK): Creation of cavity with balloon before cement injection 1
  • Both techniques provide comparable pain relief, though kyphoplasty may offer better height restoration and less cement leakage 8
  • Timing: While traditionally performed after 3 weeks of failed conservative treatment, evidence supports benefits for both acute (<6 weeks) and chronic fractures 1

Surgical Consultation

  • Reserved for patients with:
    • Neurological deficits 1, 2
    • Significant spinal deformity (>15% kyphosis) 1, 2
    • Spinal instability or retropulsion of bone fragments into spinal canal 1, 2

Follow-up and Monitoring

  • Regular assessment of pain control and functional status 9
  • Monitoring for subsequent fractures, which occur in approximately 5-8% of patients within one year 7
  • Continued management of underlying osteoporosis 9

Common Pitfalls to Avoid

  • Prolonged bed rest leading to deconditioning, bone loss, and increased mortality 1
  • Overuse of narcotics causing sedation, falls, and decreased physical conditioning 1
  • Delaying vertebral augmentation in patients with risk factors for failed conservative management 7
  • Missing unstable fractures by not performing adequate neurological examination 2
  • Neglecting treatment of underlying osteoporosis, leading to subsequent fractures 9

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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