What are the appropriate next steps in caring for a patient exposed to oleoresin capsicum (OC) spray?

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Last updated: March 25, 2025View editorial policy

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From the Guidelines

The immediate care for a patient exposed to oleoresin capsicum (OC) spray involves removing them from the exposure area and irrigating the affected areas with copious amounts of cool water or saline solution. This is based on the most recent guidelines from the American Heart Association and American Red Cross, which emphasize the importance of rapid removal of the caustic agent to minimize morbidity and mortality 1.

When caring for a patient exposed to OC spray, it is essential to:

  • Remove contaminated clothing and jewelry to avoid trapping chemicals against the skin during decontamination
  • Irrigate the affected areas with cool water or saline solution to help flush out the irritant
  • Have the patient blink repeatedly if eyes are affected to help flush out the irritant
  • Wash the skin with mild soap and water, avoiding harsh soaps or alcohol-based products which can worsen irritation
  • Irrigate the eyes with sterile saline or water for at least 15 minutes if eye exposure occurs

Symptoms can be managed with cool compresses and over-the-counter pain relievers like acetaminophen or ibuprofen. A topical anesthetic eye drop like tetracaine may provide temporary relief for severe eye pain, but should only be used once under medical supervision. Most symptoms resolve within 30-45 minutes, though eye irritation may persist for 24 hours. It is crucial to seek immediate medical attention if symptoms worsen, breathing difficulties occur, or if the patient has underlying respiratory conditions like asthma.

The key to effective first aid is to prioritize the removal of the caustic agent and to avoid contaminating other individuals or areas with the substance, as emphasized in the 2024 American Heart Association and American Red Cross guidelines for first aid 1.

From the Research

Immediate Care

  • Decontamination is a priority in treating patients exposed to oleoresin capsicum (OC) spray, as it alleviates symptoms and prevents long-lasting effects 2, 3
  • Thorough decontamination should be carefully carried out to avoid contamination of the surrounding skin and clothing 3
  • Hypertonic saline, an amphoteric surfactant, and a chelating agent may be used to treat patients immediately, resulting in substantial improvement 2

Ocular Care

  • Ocular exposure to OC spray can cause severe and permanent damage to the corneo-conjunctival tissue 4
  • Patients with ocular symptoms may require further care from an ophthalmologist and topical medication 2
  • Protective goggles may be an option when direct spraying into the face of individuals, such as in law enforcement training 5

Symptom Management

  • Symptoms of OC spray exposure include itching, irritation, burning, and pain 2
  • Treatment consists of symptom-directed supportive measures, and early detection and treatment of systemic toxicity 3
  • For acute pain management, acetaminophen or nonsteroidal anti-inflammatory drugs (NSAIDs) may be used as first-line pharmacologic agents 6

Risk Assessment

  • Factors associated with more severe outcomes include use for law enforcement training, direct intentional exposure, and law enforcement use on individual target suspects or crowd control 5
  • Patients with persistent ocular or respiratory symptoms may require transport for medical evaluation 5

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

[Injuries from pepper spray used for self defense: analysis of 15 cases managed in an emergency chemical decontamination area].

Emergencias : revista de la Sociedad Espanola de Medicina de Emergencias, 2016

Research

Clinicopathological effects of pepper (oleoresin capsicum) spray.

Hong Kong medical journal = Xianggang yi xue za zhi, 2015

Research

[Pepper spray injuries of the anterior segment of the eye].

Klinische Monatsblatter fur Augenheilkunde, 2005

Research

Pharmacologic therapy for acute pain.

American family physician, 2013

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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