From the Research
Ganaton tablets (itopride hydrochloride) are typically prescribed at a dosage of 50 mg three times daily, taken before meals, with a maximum daily dose not exceeding 150 mg, as supported by the most recent study 1. The recommended dosage is based on the latest evidence from a 2024 study published in Przeglad gastroenterologiczny, which demonstrated the efficacy and safety of itopride as an add-on therapy to a proton pump inhibitor in the treatment of gastroesophageal reflux disease 1.
Key Points to Consider
- The dosage of 50 mg three times daily is consistent across multiple studies, including those published in 2011 2, 2004 3, 2014 4, and 2004 5.
- Patients with reduced kidney or liver function may require dosage adjustments, although specific guidelines are not provided in the available evidence.
- Itopride works as a prokinetic agent by increasing acetylcholine levels and blocking dopamine D2 receptors, which helps improve gastrointestinal motility and relieves symptoms of functional dyspepsia, gastroesophageal reflux disease (GERD), and delayed gastric emptying.
- Common side effects may include mild headache, diarrhea, abdominal pain, or rash, but the most recent study 1 reported no adverse effects.
Important Considerations
- If you experience severe side effects or no improvement in symptoms after 2-4 weeks, consult your healthcare provider, as they may adjust your regimen based on your individual condition and response to the medication.
- Always follow your doctor's specific instructions regarding dosage and duration of treatment.