What can help prevent catheter line associated bloodstream infection at the time of insertion?

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Last updated: October 21, 2025View editorial policy

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Preventing Catheter Line-Associated Bloodstream Infections During Insertion

To prevent catheter line-associated bloodstream infections (CLABSI) at the time of insertion, healthcare providers should implement maximum sterile barrier precautions, use chlorhexidine-based skin antisepsis, perform proper hand hygiene, and select appropriate insertion sites while avoiding the femoral vein when possible. 1

Essential Preventive Measures During Insertion

Hand Hygiene

  • Perform proper hand hygiene with antiseptic-containing soap and water or alcohol-based hand rubs before and after catheter insertion 1
  • Remember that wearing gloves does not eliminate the need for hand hygiene 1

Maximum Sterile Barrier Precautions

  • Use maximum sterile barrier precautions including cap, mask, sterile gown, sterile gloves, and a sterile full-body drape during central line insertion 1
  • Ensure all healthcare personnel involved in the insertion procedure adhere to these precautions 1

Skin Antisepsis

  • Apply an alcoholic chlorhexidine solution containing a minimum of 2% chlorhexidine to the insertion site 1
  • Allow the antiseptic to completely dry according to manufacturer's recommendations before making the skin puncture 1
  • If chlorhexidine is contraindicated, alternatives include tincture of iodine, an iodophor, or 70% alcohol 1
  • Note that no recommendation can be made for chlorhexidine use in infants under 2 months of age due to safety concerns 1

Insertion Site Selection

  • Avoid using the femoral vein for central line placement when possible, especially in ICU settings 1, 2
  • Consider subclavian vein as the preferred site for non-tunneled catheters to minimize infection risk 1, 2
  • For infants, if upper body sites are contraindicated, tunneled femoral vein catheters with an exit site outside the diaper area may be considered 1

Education and Training Requirements

  • Ensure all healthcare personnel involved in catheter insertion and maintenance complete comprehensive education on CLABSI prevention 1
  • Conduct periodic assessments of healthcare workers' knowledge and adherence to preventive measures 1
  • Implement a credentialing process to verify competence in catheter insertion and maintenance of aseptic technique 1
  • Consider simulation training for accurate catheter insertion procedures 1, 3

Post-Insertion Care to Prevent Infection

Dressing Management

  • Cover the catheter site with either sterile gauze or sterile, transparent, semi-permeable dressing 1
  • Use gauze dressings if the patient is diaphoretic or if the site is bleeding or oozing 1
  • Replace gauze dressings every 2 days and transparent dressings at least every 7 days 1
  • Change dressings immediately if they become damp, loosened, or visibly soiled 1

Daily Patient Care

  • Consider daily chlorhexidine bathing for ICU patients over 2 months of age 1
  • Perform daily assessment of the continued need for the catheter, with prompt removal when no longer essential 1, 3
  • Replace catheters inserted during emergency situations (when aseptic technique cannot be ensured) within 48 hours 1

Catheter Hub and Port Management

  • Disinfect catheter hubs, needleless connectors, and injection ports before accessing the catheter 1, 4
  • Consider using antiseptic-containing caps or port protectors to cover needleless connectors 1, 4

Common Pitfalls and How to Avoid Them

  • Failing to allow antiseptic solution to completely dry before catheter insertion reduces its effectiveness 1, 5
  • Improper handling of the catheter hub during connection/disconnection can lead to intraluminal contamination 6
  • Submerging catheters underwater increases infection risk; protect catheters during showering 1, 7
  • Keeping catheters in place longer than clinically necessary increases infection risk 1, 3

Special Considerations

  • For high-risk patients or facilities with high CLABSI rates despite basic preventive measures, consider using chlorhexidine-impregnated sponge dressings for temporary short-term catheters 1, 4
  • In resource-limited settings, consider using closed-system collapsible IV fluid containers and needleless connectors instead of three-way stopcocks 1
  • Avoid routine administration of systemic antimicrobial prophylaxis during catheter insertion 1, 8

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Prevention of catheter-related blood stream infection.

Current opinion in critical care, 2007

Research

Central Line Care and Management: Adopting Evidence-Based Nursing Interventions.

Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses, 2021

Guideline

Foley Catheter Insertion in Patients with Betadine Allergy

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Strategies for prevention of catheter-related bloodstream infections.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1999

Guideline

Treatment for Skin Tears in Labia Due to a Catheter

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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