What should I do if I've been bitten by a mouse?

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Last updated: October 22, 2025View editorial policy

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Management of Mouse Bites

If you've been bitten by a mouse, immediately clean the wound thoroughly with soap and water and apply a virucidal agent such as povidone-iodine solution to prevent infection and potential rabies transmission. 1, 2

Immediate Wound Care

  • Clean the bite wound immediately and thoroughly with soap and water to reduce the risk of infection 1, 2
  • Apply a virucidal agent such as povidone-iodine solution to the wound 1, 2
  • Assess the wound for depth, location, and potential damage to underlying structures 3
  • For deep wounds or those on the hands, seek medical attention promptly 4

Medical Evaluation

  • Seek medical evaluation for proper wound assessment, especially for:
    • Bites on the hands or face 4
    • Deep puncture wounds 4
    • Signs of infection (redness, swelling, pain, discharge) 3
    • Immunocompromised individuals 3

Antibiotic Considerations

  • Antibiotic prophylaxis should be considered for high-risk wounds:
    • Hand bites (significantly reduces infection risk) 4
    • Deep puncture wounds 4
    • Wounds with signs of infection 3
    • Amoxicillin/clavulanate is the first-line prophylactic antibiotic for animal bites 3

Rabies Risk Assessment

  • Determine if the mouse was wild or domestic 1
  • Wild mice that bite humans should be euthanized and tested for rabies when possible 1
  • Consult with local health department about rabies risk in your area 1, 2
  • If the mouse cannot be captured for observation or testing, discuss rabies prophylaxis with your healthcare provider 2

Tetanus Prophylaxis

  • Review tetanus immunization status 5
  • Administer tetanus toxoid if vaccination is not current (more than 5 years since last dose) 5

Follow-up Care

  • Monitor the wound for signs of infection (increasing pain, redness, swelling, warmth, discharge) 3
  • Return for medical care if signs of infection develop 3
  • For severe or persistent infestations in your home, contact pest control professionals 1

Rodent Control Measures

  • Wear protective gloves (rubber, latex, vinyl, or nitrile) when handling dead rodents 1, 6
  • Use spring-loaded traps with peanut butter as bait to catch mice 1, 6
  • Double-bag dead rodents for disposal and disinfect traps before reuse 1, 6
  • Implement preventive measures to avoid future rodent infestations:
    • Store food in rodent-proof containers 1, 6
    • Eliminate clutter where rodents might nest 1, 6
    • Seal entry points greater than ¼-inch in diameter 1

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Guideline

Management of Animal Bites

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Dog and cat bites.

American family physician, 2014

Research

Antibiotic prophylaxis for mammalian bites.

The Cochrane database of systematic reviews, 2001

Research

Animal bites. Guidelines to current management.

Postgraduate medicine, 1992

Guideline

Prevention and Control of Rat-Borne Diseases

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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