Chalazion Treatment
The first-line treatment for chalazion consists of warm compresses applied to the affected eyelid for 5-10 minutes several times daily, combined with eyelid hygiene using mild soap or commercial eyelid cleansers. 1
Initial Conservative Management
- Apply warm compresses to the affected eyelid for 5-10 minutes, several times daily 1
- Clean eyelid margins with mild soap or commercial eyelid cleansers 1
- Perform gentle massage of the affected area after applying warm compresses to help express the obstructed meibomian gland 1
- Continue conservative treatment for 4-6 weeks, though complete resolution occurs in only about 18-21% of cases with conservative therapy alone 2
- Chalazia present for more than 2 months are less likely to resolve with conservative therapies and may require more invasive treatment 2
Advanced Treatment Options
For persistent chalazia that don't respond to conservative management:
- Intralesional steroid injection (triamcinolone acetonide) is recommended for persistent chalazia, with resolution rates of approximately 84% 3
- Incision and curettage is highly effective with resolution rates of about 87%, but may cause more pain than steroid injections 3
- Intense pulsed light (IPL) with meibomian gland expression shows promise as a non-surgical treatment option for recurrent multiple chalazia 4
Warning Signs Requiring Further Evaluation
- Recurrence in the same location raises suspicion for sebaceous carcinoma, especially in elderly patients 1, 4
- Marked asymmetry, resistance to therapy, or unifocal recurrent chalazia require further evaluation 1
- Atypical features such as eyelid margin distortion, lash loss, or ulceration necessitate biopsy 4, 5
- Unilateral chronic blepharitis unresponsive to therapy may be associated with carcinoma 1, 6
Special Considerations
- Children with chalazia may have underlying chronic blepharokeratoconjunctivitis that requires evaluation by an ophthalmologist 6, 4
- Recurrent chalazia may be associated with underlying conditions like meibomian gland dysfunction, rosacea, seborrheic dermatitis, or even subclinical hypothyroidism 6, 7
- Patients treated with corticosteroid injections should be re-evaluated within a few weeks to assess response and check intraocular pressure 4
Prevention Strategies
- Regular eyelid hygiene for patients with blepharitis or meibomian gland dysfunction 1, 6
- Treatment of underlying skin conditions (rosacea, seborrheic dermatitis) 6
- Avoiding eye makeup during active inflammation 6
- More aggressive eyelid hygiene regimen for patients with recurrent chalazia 1
Treatment Algorithm
- First 4-6 weeks: Conservative management with warm compresses, eyelid hygiene, and gentle massage
- If no improvement after 4-6 weeks: Progress to either intralesional steroid injection or incision and curettage
- For recurrent chalazia: Consider biopsy to rule out malignancy, especially in elderly patients or with atypical features 4, 5
- For multiple recurrent chalazia: Consider evaluation for underlying conditions and intense pulsed light therapy 4