What is the treatment for a chalazion?

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Chalazion Treatment

The first-line treatment for chalazion consists of warm compresses applied to the affected eyelid for 5-10 minutes several times daily, combined with eyelid hygiene using mild soap or commercial eyelid cleansers. 1

Initial Conservative Management

  • Apply warm compresses to the affected eyelid for 5-10 minutes, several times daily 1
  • Clean eyelid margins with mild soap or commercial eyelid cleansers 1
  • Perform gentle massage of the affected area after applying warm compresses to help express the obstructed meibomian gland 1
  • Continue conservative treatment for 4-6 weeks, though complete resolution occurs in only about 18-21% of cases with conservative therapy alone 2
  • Chalazia present for more than 2 months are less likely to resolve with conservative therapies and may require more invasive treatment 2

Advanced Treatment Options

For persistent chalazia that don't respond to conservative management:

  • Intralesional steroid injection (triamcinolone acetonide) is recommended for persistent chalazia, with resolution rates of approximately 84% 3
  • Incision and curettage is highly effective with resolution rates of about 87%, but may cause more pain than steroid injections 3
  • Intense pulsed light (IPL) with meibomian gland expression shows promise as a non-surgical treatment option for recurrent multiple chalazia 4

Warning Signs Requiring Further Evaluation

  • Recurrence in the same location raises suspicion for sebaceous carcinoma, especially in elderly patients 1, 4
  • Marked asymmetry, resistance to therapy, or unifocal recurrent chalazia require further evaluation 1
  • Atypical features such as eyelid margin distortion, lash loss, or ulceration necessitate biopsy 4, 5
  • Unilateral chronic blepharitis unresponsive to therapy may be associated with carcinoma 1, 6

Special Considerations

  • Children with chalazia may have underlying chronic blepharokeratoconjunctivitis that requires evaluation by an ophthalmologist 6, 4
  • Recurrent chalazia may be associated with underlying conditions like meibomian gland dysfunction, rosacea, seborrheic dermatitis, or even subclinical hypothyroidism 6, 7
  • Patients treated with corticosteroid injections should be re-evaluated within a few weeks to assess response and check intraocular pressure 4

Prevention Strategies

  • Regular eyelid hygiene for patients with blepharitis or meibomian gland dysfunction 1, 6
  • Treatment of underlying skin conditions (rosacea, seborrheic dermatitis) 6
  • Avoiding eye makeup during active inflammation 6
  • More aggressive eyelid hygiene regimen for patients with recurrent chalazia 1

Treatment Algorithm

  1. First 4-6 weeks: Conservative management with warm compresses, eyelid hygiene, and gentle massage
  2. If no improvement after 4-6 weeks: Progress to either intralesional steroid injection or incision and curettage
    • Choose steroid injection for less pain and inconvenience 3
    • Choose incision and curettage for slightly higher resolution rate 3
  3. For recurrent chalazia: Consider biopsy to rule out malignancy, especially in elderly patients or with atypical features 4, 5
  4. For multiple recurrent chalazia: Consider evaluation for underlying conditions and intense pulsed light therapy 4

References

Guideline

Chalazion and Hordeolum Treatment Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Treatment of Chalazion

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Chalazion and Hordeolum Management

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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