What is the best course of action for a 16-year-old female with insomnia (difficulty initiating or maintaining sleep) that is refractory (unresponsive) to sleep hygiene measures?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 26, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the Guidelines

For a 16-year-old female with insomnia that hasn't responded to sleep hygiene measures, I strongly recommend starting with cognitive behavioral therapy for insomnia (CBT-I) as the first-line treatment, as it has the most evidence available in the literature and is the only approach to receive a Strong recommendation 1.

Key Components of CBT-I

  • Stimulus control
  • Sleep restriction
  • Relaxation techniques
  • Cognitive restructuring to address unhelpful thoughts about sleep CBT-I is a multicomponent intervention that has been shown to be effective in improving sleep and alleviating distress or dysfunction caused by insomnia 1.

Considerations for Treatment

  • Availability and accessibility of CBT-I providers
  • Patient preferences and values
  • Comorbid medical and psychiatric conditions that may impact treatment
  • Potential undesirable effects of treatment, such as sleepiness and fatigue It's essential to discuss different CBT-I delivery modalities with the patient, including in-person individual or group treatment, internet-based programs, and align the delivery modality based on availability, affordability, treatment format, duration, and the patient's preferences and values 1.

Additional Recommendations

  • Rule out underlying conditions like depression, anxiety, ADHD, or sleep disorders that might be causing the insomnia
  • Screen for substance use, including caffeine, alcohol, and recreational drugs
  • Evaluate for potential medication side effects if the patient is taking any Regular follow-up is crucial to monitor response and adjust treatment, as the adolescent brain is still developing, making non-pharmacological approaches preferable when possible, but targeted medication can be appropriate when insomnia significantly impacts daily functioning, mood, and academic performance.

From the FDA Drug Label

PRINCIPAL DISPLAY PANEL - Vitamin Bottle Label Safrel Melatonin 3mg Tablets: Helps establish normal sleep patterns 100%Drug-free and non-habit forming melatonin is a nighttime sleep aid for occassional sleeplessness.

The FDA drug label does not answer the question.

From the Research

Treatment Options for Insomnia

For a 16-year-old female with insomnia that is refractory to sleep hygiene measures, the following treatment options can be considered:

  • Cognitive Behavioral Therapy for Insomnia (CBT-I) as the first line treatment 2, 3, 4
  • Sleep restriction therapy, which has been found to be an effective component of CBT-I 5
  • Stimulus control therapy, which can improve self-reported and objective total sleep time 5
  • Relaxation training and cognitive therapy, which are also components of CBT-I 2, 3, 4

Considerations for Adolescents

When treating insomnia in adolescents, it is recommended to:

  • Integrate parents into the treatment, especially for school-aged children with insomnia 6
  • Consider the specific characteristics and models of child and adolescent insomnia, as more research is needed in this area 6

Delivery of CBT-I

CBT-I can be delivered in various ways, including:

  • Individual sessions 2, 3
  • Group sessions 3
  • Online or digital platforms 4

Efficacy of CBT-I

CBT-I has been found to be an effective treatment for insomnia, with significant improvements in:

  • Sleep onset latency 4
  • Wakefulness after sleep 4
  • Sleep efficiency 4
  • Sleep quality 4

References

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Cognitive-behavioral therapy for chronic insomnia.

Current treatment options in neurology, 2014

Research

Cognitive Behavioral Therapy for Insomnia (CBT-I): A Primer.

Klinicheskaia i spetsial'naia psikhologiia = Clinical psychology and special education, 2022

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.