What is the estimated amount of mupirocin (Bactroban) used in 14 applications?

Amount of Mupirocin in 14 Applications

The estimated amount of mupirocin used in 14 applications is approximately 7-14 grams, based on standard dosing recommendations for nasal decolonization protocols.

Mupirocin Dosing Information

• Standard mupirocin ointment (Bactroban) is available as a 2% formulation in a polyethylene glycol base for topical application 1
• For nasal decolonization protocols, mupirocin is typically applied twice daily to both nostrils for 5-7 days 2
• Each application typically uses approximately 0.5-1 gram of ointment (divided between both nostrils) 3
• Therefore, 14 applications would require approximately 7-14 grams of mupirocin ointment 3, 4

Clinical Usage Patterns

• For Staphylococcus aureus nasal decolonization, the most common protocol involves:

  • Two daily applications of 2% mupirocin for 5-7 days 2
  • This equals 10-14 total applications per treatment course 2
  • Often combined with chlorhexidine bathing for maximum effectiveness 2

• For skin infections such as impetigo, the standard regimen is:

  • Three times daily application for approximately 7-10 days 1
  • This equals 21-30 total applications per treatment course 1

Practical Considerations

• Mupirocin is packaged in tubes of various sizes (15g, 22g, 30g) 4
• A 15g tube typically contains enough medication for one complete course of nasal decolonization treatment 3
• For skin infections requiring more extensive application, larger tubes may be necessary 1
• The amount used per application varies based on the size of the area being treated 1

Efficacy Considerations

• Proper application technique is crucial for effectiveness 2
• For nasal decolonization, mupirocin has shown excellent efficacy with over 95% elimination of S. aureus, including MRSA 3
• For skin infections, clinical cure or improvement is typically seen in over 90% of patients 1