From the Research
Forms of Magnesium and Blood Pressure
- The provided studies do not specifically compare the effects of different forms of magnesium on blood pressure 1, 2, 3, 4, 5.
- However, the studies suggest that magnesium supplementation can have a small to moderate effect on lowering blood pressure, depending on the dose and population being studied 2, 3, 4.
Magnesium Dose and Blood Pressure
- A meta-analysis of 20 randomized clinical trials found that magnesium supplementation resulted in a small overall reduction in blood pressure, with a pooled net estimate of -0.6 mm Hg for systolic BP and -0.8 mm Hg for diastolic BP 3.
- However, the same study found a dose-dependent effect of magnesium, with reductions of 4.3 mm Hg systolic BP and 2.3 mm Hg diastolic BP for each 10 mmol/day increase in magnesium dose 3.
- Another study found that oral magnesium doses of ≥240 mg/day safely lowered BP in Uncontrolled Hypertensive patients taking antihypertensive medications, while >600 mg/day magnesium was required to safely lower BP in Untreated Hypertensives 4.
Magnesium and Cardiovascular Health
- Magnesium supplementation has been shown to have other beneficial effects on cardiovascular health, including improving insulin sensitivity, hyperglycemia, diabetes mellitus, left ventricular hypertrophy, and dyslipidemia 1, 5.
- Magnesium also increases the effectiveness of all antihypertensive drug classes and acts as a natural calcium channel blocker, increases nitric oxide, improves endothelial dysfunction, and induces direct and indirect vasodilation 1.