From the Research
Management of Retinal Macroaneurysm
The management of retinal macroaneurysm can be varied and depends on the symptoms and complications associated with the condition.
- Treatment options may include:
- Observation alone for lesions not threatening the fovea 1
- Laser photocoagulation for exudative or hemorrhagic complications 2, 3, 1, 4
- Intravitreal injection of vascular endothelial growth factor (VEGF) inhibitors for exudative or hemorrhagic complications 2, 1
- Vitrectomy, gas, and yttrium aluminum garnet (YAG) laser for hemorrhagic complications 3, 1
- Tissue plasminogen activator (tPA) for hemorrhagic complications 1
- The use of multimodal imaging, including optical coherence tomography angiography (OCT-A), can help in diagnosing and managing retinal arterial macroaneurysms 1
- Each case requires individual consideration, and a uniform therapeutic recommendation is still yet to be developed 5
- It is essential to refer patients to internal medicine for management of underlying systemic conditions, such as hypertension and arteriosclerosis 5
- The goal of treatment is to prevent vision loss and improve visual outcomes, with logMAR visual acuity improvement reported in some studies 3