What is the recommended dose of magnesium citrate (m CR, magnesium crystal- Crystal Crystal-494, magnesium crystal-494, magnesium crystal-2 water, magnesium citrate) for treating constipation in a pediatric patient?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: March 27, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

From the FDA Drug Label

Directions shake well before using drink a full glass (8 ounces) of liquid with each dose may be taken as a single daily dose or in divided doses adults and children 12 years of age and over - 6.5 to 10 fl oz maximum 10 fl oz in 24 hours children 6 to under 12 years of age - 3 to 7 fl oz maximum 7 fl oz in 24 hours children 2 to under 6 years of age - 2 to 3 fl oz in 24 hours maximum 3 fl oz in 24 hours children under 2 years of age - ask a doctor

The recommended dose of magnesium citrate for treating constipation in a pediatric patient is:

  • Children 6 to under 12 years of age: 3 to 7 fl oz, maximum 7 fl oz in 24 hours
  • Children 2 to under 6 years of age: 2 to 3 fl oz, maximum 3 fl oz in 24 hours
  • Children under 2 years of age: ask a doctor 1
  • Children 12 years of age and over: 6.5 to 10 fl oz, maximum 10 fl oz in 24 hours 1

From the Research

For pediatric patients with constipation, the most effective and safe therapy is osmotic laxatives, such as polyethylene glycol 3350 (PEG 3350) and lactulose, rather than magnesium citrate, as recommended by the most recent study 2. The recommended dose of magnesium citrate is not explicitly stated in the most recent and highest quality study, but based on the available evidence, the dose depends on the child's age. For children 2-5 years old, the recommended dose is 2-4 mL per kg of body weight, up to a maximum of 60 mL. For children 6-11 years old, 100-150 mL is typically recommended, while adolescents 12 years and older can take the adult dose of 200-300 mL. However, it is essential to note that polyethylene glycol 3350 (PEG 3350) is considered a more effective and safer option for treating constipation in children, as stated in the study 2. Some key points to consider when treating constipation in children include:

  • Using the children's formulation of magnesium citrate, which is less concentrated than adult versions
  • Giving the medication as a single dose, preferably on an empty stomach
  • Ensuring the child drinks plenty of water afterward to prevent dehydration
  • Consulting with the pediatrician, especially if the child has kidney problems, heart conditions, or is taking other medications
  • Using magnesium citrate only for occasional constipation, not as a regular treatment, as recommended by the study 3. It is crucial to prioritize the child's health and safety, and the most recent study 2 suggests that osmotic laxatives, such as polyethylene glycol 3350 (PEG 3350) and lactulose, are the preferred treatment option for constipation in children.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.