What is a low dose magnesium intake?

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From the FDA Drug Label

each fl oz contains: magnesium 290 mg DIRECTIONS Antacid Directions:■ take 1 tablet twice a day or as directed by a physician Magnesium Supplement Directions: ■take 1 to 2 tablets daily or as directed by a physician

The FDA drug label does not answer the question.

From the Research

A low dose magnesium intake is typically considered to be less than 250 mg per day, as deficient intakes at this level have been associated with elevated serum C-reactive protein concentration, a widely used indicator of inflammation, as noted in a study published in 2014 1. When considering magnesium intake, it's essential to understand that magnesium is an essential mineral involved in numerous physiological processes, including energy production, protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation.

  • Insufficient magnesium intake can lead to various health issues such as muscle cramps, fatigue, irregular heartbeat, and potentially increased risk of chronic conditions like hypertension and osteoporosis.
  • The recommended daily amount of magnesium is approximately 310-320 mg for women and 400-420 mg for men, as suggested by various studies, including one published in 2016 2.
  • If you're considering magnesium supplementation, start with a low dose of about 100 mg daily and gradually increase as needed, preferably under healthcare supervision, as excessive intake can lead to hypermagnesemia, which can be a potential threat, especially in individuals with inadequate renal function, as discussed in a study from 1991 3.
  • Common supplement forms include magnesium citrate, glycinate, and oxide, with citrate and glycinate generally being better absorbed, and taking magnesium with food can help reduce potential digestive side effects like diarrhea.
  • Always consult with a healthcare provider before starting any supplement regimen, especially if you have kidney disease or take medications that might interact with magnesium, as emphasized in a study published in 2010 4 and another in 2018 5.

References

Research

Effects of magnesium depletion on inflammation in chronic disease.

Current opinion in clinical nutrition and metabolic care, 2014

Research

Magnesium: Nutrition and Homoeostasis.

AIMS public health, 2016

Research

Magnesium in perinatal care and infant health.

Magnesium and trace elements, 1991

Research

Hypomagnesemia: an evidence-based approach to clinical cases.

Iranian journal of kidney diseases, 2010

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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