Management of Urinary Obstruction with Gross Hematuria Requiring Foley Catheterization
In patients with urinary obstruction and gross hematuria, place a large-bore (18-22 Fr) three-way Foley catheter with continuous bladder irrigation to prevent clot obstruction, while simultaneously investigating the underlying cause of bleeding. 1
Immediate Catheterization Strategy
Catheter Selection and Placement
- Use a larger caliber three-way catheter (18-22 Fr) rather than standard size (14-16 Fr) when gross hematuria is present to accommodate clot passage and allow continuous bladder irrigation 1, 2
- Standard 14-16 Fr catheters are appropriate only for clear urine or minimal hematuria 2
- Replace any existing catheter that becomes obstructed with clots with an appropriately larger-sized catheter to ensure adequate drainage 1
Critical Pre-Catheterization Assessment
- Do NOT attempt urethral catheterization if blood is present at the urethral meatus in trauma patients—perform retrograde urethrography first 3, 4
- In pelvic fracture patients with gross hematuria, retrograde cystography must be performed to evaluate for bladder injury 4
- The combination of gross hematuria and pelvic fracture indicates bladder injury in 29% of cases, making imaging mandatory 4
Continuous Bladder Irrigation Protocol
When to Initiate CBI
- Start continuous bladder irrigation immediately if hematuria is severe enough to form clots or obstruct the catheter 1
- Use normal saline at a rate sufficient to keep output light pink to clear (typically 200-500 mL/hour initially, adjusted based on output color) 1
- Monitor for signs of clot retention: decreased output, bladder distention, suprapubic pain, or catheter obstruction 1
Managing Persistent Clot Obstruction
- If clots continue to obstruct despite CBI, perform manual bladder irrigation with a large syringe (60 mL) using gentle pressure 1
- Never forcefully irrigate against resistance—this may indicate catheter malposition or bladder injury 5, 6
- Consider cystoscopy with clot evacuation if conservative measures fail 7
Investigating the Underlying Cause
Infection-Related Hematuria
- Obtain urine culture before initiating antibiotics in all patients with catheter-associated hematuria 1
- Urinary tract infection is a common cause of catheter-associated hematuria, but gross hematuria warrants further investigation beyond treating infection alone 1, 4
Trauma-Related Considerations
- Gross hematuria with pelvic fracture requires retrograde cystography (plain film or CT) with minimum 300 mL bladder filling to diagnose bladder rupture 4
- Intraperitoneal bladder rupture requires immediate surgical repair 4
- Extraperitoneal bladder injuries may be managed conservatively with catheter drainage alone 4
Catheter Trauma vs. Pathologic Bleeding
- Catheter-induced hematuria typically causes minimal bleeding (fewer than 4 RBCs per high-power field in most patients) 8
- Gross hematuria should never be attributed to catheterization alone—it indicates underlying pathology requiring investigation 8, 4
- In neurogenic bladder patients with indwelling catheters, gross hematuria requires upper tract imaging (CT urogram or renal ultrasound) and cystoscopy to evaluate for bladder cancer, stones, or anatomic abnormalities 4
High-Risk Scenarios Requiring Specialist Consultation
Immediate Urologic Consultation Needed
- Persistent gross hematuria despite catheter placement and continuous bladder irrigation 1
- Suspected bladder injury in trauma patients (pelvic fracture with gross hematuria, penetrating injury) 4
- Inability to pass catheter or suspected urethral injury (blood at meatus, false passage) 3
- Hemodynamic instability or signs of ongoing blood loss requiring transfusion 7
Suprapubic Catheter Consideration
- Place suprapubic tube instead of urethral catheter when complete urethral disruption is confirmed on urethrography 3
- Consider suprapubic catheterization if repeated urethral catheter attempts fail or cause additional trauma 3, 5
Critical Pitfalls to Avoid
Catheterization Errors
- Avoid using undersized catheters (14-16 Fr) in gross hematuria—they will obstruct with clots 1, 2
- Do not make repeated forceful catheterization attempts, which can create false passages and worsen bleeding 3, 5
- Never inflate the balloon until urine return confirms proper bladder placement 5, 6
Decompressive Hematuria Risk
- In patients with chronic urinary retention and massive bladder distention, rapid decompression can cause severe decompressive hematuria requiring transfusion and prolonged hospitalization 7
- While complete obstruction requires immediate drainage, be prepared for potential massive hematuria and have resuscitation resources available 7
Coagulopathy Considerations
- In patients with sepsis and disseminated intravascular coagulation, Foley catheterization carries risk of life-threatening hemorrhage from friable urethral tissue 9
- Correct coagulopathy before catheterization when possible, or use smallest appropriate catheter with extreme gentleness 9
Monitoring and Follow-Up
Acute Phase Monitoring
- Monitor catheter output hourly for volume, color, and clot passage 1
- Check hemoglobin/hematocrit if bleeding is substantial or patient shows signs of anemia 7
- Maintain catheter drainage until hematuria resolves, particularly after transurethral procedures 1