Chocolate Ingestion in Dogs: Immediate Veterinary Assessment Required
If a dog eats chocolate, immediate veterinary intervention is critical because chocolate contains theobromine and caffeine—methylxanthine alkaloids that are potentially lethal to dogs due to their prolonged 18-hour half-life in canines, compared to just 2-3 hours in humans. 1
Mechanism of Toxicity
Theobromine accumulates in dogs because they metabolize it extremely slowly, undergoing hepatic metabolism with extrahepatic recirculation before urinary excretion. 1 This prolonged exposure affects multiple organ systems:
- Central nervous system: Hyperexcitability, hyperirritability, tremors, seizures 1
- Cardiovascular system: Sinus tachycardia, cardiac arrhythmias 1
- Respiratory system: Tachypnea, excessive panting 1
- Renal system: Diuretic effects leading to polyuria/polydipsia 1
Clinical Presentation Timeline
Symptoms typically begin within 2 hours of ingestion but may be delayed up to 24 hours, with recovery potentially taking up to 3 days due to slow theobromine metabolism. 1
Early Signs (First 2-6 Hours)
Progressive Signs
- Tremors and muscle twitching 1
- Hyperthermia 2
- Ataxia 1
- Cardiac arrhythmias 1
- Seizures and potential death 1
Risk Assessment by Chocolate Type
The lethal dose of theobromine is 100-500 mg/kg body weight, but toxicity varies dramatically by chocolate type. 1
Theobromine Concentration by Type:
- Cocoa powder: 20 mg/g (highest risk) 1
- Dark/plain chocolate: 15 mg/g 1
- Milk chocolate: 2 mg/g 1
- White chocolate: 0.1 mg/g (minimal risk) 1
Critical calculation: Less than 100 grams of dark chocolate can be fatal for a 10 kg dog. 1 In a recent case series, 28 of 44 symptomatic dogs had ingested dark or bitter chocolate. 2
Laboratory Findings
When clinical pathology is performed, expect: 2
- Hyperlactataemia (most common metabolic derangement)
- Hypokalaemia (from excessive urinary losses)
- Mild hyperglycaemia (stress response)
- Elevated ALT and AST (hepatic involvement)
Immediate Management Protocol
There is no specific antidote for theobromine toxicity—treatment is entirely supportive. 1
Decontamination (if within 2-4 hours of ingestion):
Supportive Care:
- Intravenous fluid therapy for hydration and forced diuresis 1
- Esmolol for tachycardia and cardiac arrhythmias 2
- Sedatives (benzodiazepines) for tremors and seizures 2
- Oxygen supplementation as needed 1
- Temperature management for hyperthermia 2
Prognosis
With prompt decontamination and aggressive supportive care, prognosis is excellent—mortality rate is less than 3%. 2 In a recent series of 156 chocolate ingestion cases, 43 of 44 symptomatic dogs survived with appropriate treatment. 2
However, 112 of 156 dogs (72%) remained asymptomatic, emphasizing that not all chocolate ingestions result in clinical toxicity. 2 The outcome depends critically on:
- Type of chocolate ingested (dark > milk > white) 1
- Amount consumed relative to body weight 1
- Time elapsed before treatment 1
Critical Pitfalls to Avoid
Do not wait for symptoms to develop before seeking veterinary care—the 18-hour half-life means theobromine continues accumulating even after ingestion stops. 1
Cocoa shell mulch in gardens poses an equal threat (25 mg/g theobromine concentration) and may attract dogs due to its chocolate aroma. 1
Never assume small amounts are safe—even "occasional small treats" carry risk, and pet-specific chocolate substitutes without theobromine should be used instead. 1