What is a normal right ventricle (RV) to left ventricle (LV) ratio?

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Last updated: November 18, 2025View editorial policy

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Normal RV:LV Ratio

A normal RV:LV ratio is <1.0, with values ≥1.0 indicating right ventricular dilation and associated with significantly worse prognosis. 1

Standard Measurement Thresholds

Primary Cutoff Values

  • An RV/LV ratio <1.0 is considered normal across multiple European Society of Cardiology guidelines for pulmonary embolism assessment 1
  • The 2019 ESC guidelines specifically illustrate that dilated RV with basal RV/LV ratio >1.0 represents pathologic right ventricular enlargement 1
  • Some studies have used RV/LV ratio >0.9 as the threshold for identifying RV dilation, which showed 64% prevalence in PE patients and strong prognostic value 1

Measurement Technique

  • The ratio should be measured in the four-chamber view from reformatted CT images or echocardiography, measuring the maximum diameter perpendicular to the long axis of each ventricle 1
  • On CT imaging, measure the distance between the ventricular endocardium and the interventricular septum, perpendicular to the heart's long axis 2
  • Measurements are typically obtained at the basal level (widest diameter) in end-diastole 1

Clinical Significance and Prognostic Value

Mortality Risk Stratification

  • RV/LV ratio >1.0 combined with vascular obstruction >40% increases 3-month PE-related mortality to 18.8% in the MAPPET registry 1
  • The negative predictive value of RV/LV >1.0 for uneventful outcome was 100% (95% CI, 94.3-100%), meaning a normal ratio essentially excludes high-risk PE 1
  • In intermediate-risk PE, patients with RV/LV ratio <1.03 and preserved RV function had only 1.0% 30-day mortality, while those with RV/LV ≥1.03 and impaired function had 46.2% mortality 3

Volume-Based Severity Grading

  • For severe RV dilation using volume ratios, RV/LV volume ratio ≥2.30 defines severe dilation and is associated with significantly higher mortality in pulmonary hypertension 4
  • Moderate dilation corresponds to RV/LV volume ratio 1.70-2.29, and mild dilation to 1.27-1.69 4
  • These volume-based thresholds differ from diameter ratios but provide outcome-based severity grading 4

Important Clinical Caveats

Measurement Reliability

  • After simple instruction, RV/LV diameter ratio assessment is accurate and reproducible even by residents without CTPA experience, with kappa statistics of 0.83-0.94 compared to experienced radiologists 2
  • The average interobserver difference is minimal (SD 0.11-0.18), making this a practical bedside or radiologic assessment 2

Context-Dependent Interpretation

  • RV/LV ratio >1.0 indicates RV dysfunction specifically in the context of acute PE, where it reflects acute pressure overload 1
  • In chronic conditions, the American Heart Association notes that RV adaptation to chronic pressure overload may maintain function despite dilation, requiring integration with other parameters like TAPSE and strain imaging 1
  • The ratio must be interpreted alongside clinical hemodynamics, biomarkers (BNP/NT-proBNP), and other echocardiographic findings such as septal flattening and tricuspid regurgitation 1

Pitfalls to Avoid

  • Do not rely on RV/LV ratio alone—10% of PE patients may have misleading findings such as significant LV dysfunction or valvular disease that affect interpretation 1
  • Severe tricuspid regurgitation can cause RV dilation independent of pressure overload, potentially overestimating dysfunction 1, 5
  • In mechanically ventilated patients, altered intrathoracic pressures limit reliability of RV assessment 5

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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