Which EKG (electrocardiogram) leads are used to assess the right side of the heart?

Medical Advisory BoardAll articles are reviewed for accuracy by our Medical Advisory Board
Educational purpose only • Exercise caution as content is pending human review
Article Review Status
Submitted
Under Review
Approved

Last updated: November 19, 2025View editorial policy

Personalize

Help us tailor your experience

Which best describes you? Your choice helps us use language that's most understandable for you.

EKG Leads for Right Heart Assessment

For assessing the right side of the heart, use right-sided precordial leads V3R and V4R, with V4R being the single most valuable lead, positioned in the 5th intercostal space at the right midclavicular line. 1

Standard 12-Lead Assessment

In the standard 12-lead EKG, lead V1 provides the best view of right ventricular activity among the routine leads, as it sits closest to the right ventricle anatomically. 2 However, V1 alone has limited sensitivity and specificity for right ventricular pathology. 3

Right-Sided Precordial Leads (The Gold Standard)

The American Heart Association and American College of Cardiology recommend four additional right-sided precordial leads for comprehensive right heart evaluation: 2

  • V3R and V4R are the most clinically useful, positioned as mirror images of V3 and V4 on the right anterior chest wall 1
  • V4R specifically is positioned in the 5th intercostal space at the right midclavicular line and has the greatest diagnostic value 1
  • V1R and V2R (where standard V1 = V1R and standard V2 = V2R) 2
  • V5R and V6R complete the right-sided array 2

Critical Clinical Application: Right Ventricular Infarction

Right-sided leads are essential for detecting right ventricular infarction, which complicates approximately 25% of inferior wall myocardial infarctions. 4 The diagnostic approach follows this algorithm:

When to Obtain Right-Sided Leads

Record V3R and V4R immediately in ALL patients with ST elevation in leads II, III, and aVF (inferior MI). 1, 5 This is a joint recommendation from the American Heart Association and American College of Cardiology. 1

Diagnostic Criteria

  • ST elevation ≥0.1 mV (1 mm) in V3R or V4R indicates right ventricular involvement 2
  • This finding is moderately sensitive and specific for right ventricular injury 2
  • Often accompanied by ST elevation in standard lead V1 1, 5

Critical Timing Pitfall

ST elevation in right-sided leads disappears much faster than in inferior leads—you must record V3R and V4R as rapidly as possible after chest pain onset. 1, 6 This is the single most important pitfall to avoid, as delayed recording may miss the diagnosis entirely. 1

Additional Diagnostic Clues in Standard Leads

When right ventricular infarction occurs with inferior MI, look for these patterns in the standard 12-lead:

  • ST elevation greater in lead III than lead II suggests right coronary artery occlusion (which supplies the RV in most patients) 5, 7
  • ST elevation in V1 may indicate RV involvement 1, 5, 4
  • ST depression in leads I and aVL often accompanies RCA occlusion 6

Practical Implementation

Modern ECG machines should be programmed to automatically suggest recording V3R and V4R when ST elevation >0.1 mV occurs in leads II, III, and aVF. 1 If your machine doesn't do this automatically, develop a protocol to manually obtain these leads in all inferior STEMI cases.

Clinical Significance

Identifying right ventricular infarction has major implications for mortality and management:

  • Patients with RV infarction have markedly worse prognosis compared to isolated inferior MI 4
  • RV failure makes left ventricular filling entirely preload-dependent 4
  • Avoid nitroglycerin and use morphine judiciously, as these reduce preload and can cause severe hypotension 4
  • Aggressive IV fluid resuscitation is the cornerstone of management 4
  • V4R helps distinguish proximal versus distal RCA occlusion, which has prognostic and therapeutic implications 1

References

Guideline

Right Ventricle Electrocardiography

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

The electrocardiogram in right ventricular myocardial infarction.

The American journal of emergency medicine, 2005

Guideline

Inferior Leads on ECG

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Management of Rightward Axis ST Changes in Inferior Leads

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Identifying the culprit artery via 12-lead electrocardiogram in inferior wall ST-segment elevation myocardial infarction: A meta-analysis.

Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2023

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

Have a follow-up question?

Our Medical A.I. is used by practicing medical doctors at top research institutions around the world. Ask any follow up question and get world-class guideline-backed answers instantly.