From the Research
Tadalafil is likely a safer option than sildenafil for patients with tachycardia or cardiovascular concerns due to its more gradual onset and longer duration of action, which typically results in less pronounced cardiovascular effects. Both tadalafil and sildenafil can potentially cause tachycardia (increased heart rate) as a side effect, though this is relatively uncommon. Sildenafil (Viagra) may be slightly more likely to cause tachycardia than tadalafil (Cialis) due to its shorter half-life and more rapid onset of action 1.
Some key points to consider when choosing between tadalafil and sildenafil for patients with tachycardia or cardiovascular concerns include:
- Tadalafil stays in your system longer (half-life of 17.5 hours versus 4 hours for sildenafil), allowing for once-daily dosing and potentially smoother cardiovascular effects 2.
- Both medications work by inhibiting phosphodiesterase type 5 (PDE5), increasing blood flow to the penis, but they can also cause vasodilation elsewhere in the body, potentially affecting heart rate 3.
- Neither medication should be taken with nitrates or certain other cardiovascular medications, as this combination can cause dangerous drops in blood pressure 4.
- The acute, short-term effects of oral sildenafil on blood pressure and heart rate in men with erectile dysfunction were small and not likely to be clinically significant in those taking concomitant antihypertensive medication 5.
It's essential to consult a healthcare provider before taking either medication, especially if you have pre-existing tachycardia or cardiovascular concerns, to determine the best course of treatment and minimize potential risks. If you experience persistent tachycardia with either medication, consult your healthcare provider immediately, as this could indicate an adverse reaction.