How do you interpret an electrocardiogram (EKG)?

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Last updated: November 27, 2025View editorial policy

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How to Read an EKG: A Systematic Approach

Use a systematic, step-by-step method to interpret every EKG, starting with rate and rhythm, then progressing through intervals, axis, and waveform morphology—always correlating findings with the patient's clinical presentation. 1

Step 1: Calculate Heart Rate

  • Count the number of large boxes between consecutive R waves and divide 300 by this number, or count QRS complexes in a 6-second strip and multiply by 10 1, 2
  • Normal sinus rhythm: 60-100 beats per minute in adults 1, 3
  • Sinus bradycardia (<60 bpm) may be normal in athletes 1, 3
  • Sinus tachycardia (>100 bpm) may occur during physiological stress 1

Step 2: Identify the Rhythm

  • Look for a P wave before each QRS complex with a consistent PR interval to confirm sinus rhythm 1, 3
  • Examine R-R intervals for regularity 2
  • Note any irregularities such as premature beats, pauses, or completely irregular patterns suggesting atrial fibrillation 1
  • Identify the underlying rhythm origin (sinus, atrial, junctional, or ventricular) based on P wave morphology and relationship to QRS complexes 2

Step 3: Measure Intervals

  • PR interval: Normal is 120-200 ms (3-5 small squares) to assess AV conduction 1, 2, 3
  • QRS duration: Normal is <120 ms (<3 small squares) to evaluate ventricular conduction 1, 2, 3
  • QTc (corrected QT): Normal is <450 ms for men, <460 ms for women using Bazett's formula 1, 2, 3
  • Measure QT interval manually in lead II or V5 using the teach-the-tangent method 3

Step 4: Determine Electrical Axis

  • Examine leads I and aVF to quickly determine the axis quadrant 1, 2
  • Normal axis: +90° to -30° (positive in both leads I and aVF) 1, 2
  • Left axis deviation: -30° to -90° (positive in lead I, negative in aVF) 1, 2
  • Right axis deviation: +90° to +180° (negative in lead I, positive in aVF) 1, 2
  • Extreme axis deviation: +180° to -90° (negative in both leads I and aVF) 1

Step 5: Analyze Waveform Morphology

P Waves

  • Normal P waves are upright in leads I, II, aVF and biphasic in V1 2
  • Duration should be <120 ms and amplitude <2.5 mm 2
  • Abnormalities suggest atrial enlargement 1, 2

QRS Complexes

  • Look for pathological Q waves (>0.04 seconds or >25% of R wave amplitude) suggesting myocardial infarction 1, 2
  • Assess R wave progression across precordial leads—amplitude should increase from V1 to V4, then decrease toward V6 2
  • Check voltage criteria for left ventricular hypertrophy: S in V1 + R in V5 or V6 >3.5 mV (Sokolow-Lyon criterion) 1

ST Segments and T Waves

  • Examine ST segments for elevation (>0.1 mV in limb leads or >0.15-0.2 mV in precordial leads) indicating acute injury 1, 2
  • Look for ST depression suggesting ischemia 2
  • T waves should be upright in leads I, II, V3-V6, inverted in aVR, and variable in III, aVL, aVF, V1, and V2 2
  • Note T wave abnormalities (inversion, hyperacute, flattening) 1

Step 6: Identify Location of Abnormalities

  • Note which leads show abnormalities to determine the affected coronary territory 1
  • This localizes ischemia, injury, or infarction to specific cardiac regions 1

Step 7: Consider Special Factors

  • Age and gender affect normal parameters—QT intervals are typically longer in women 2
  • T waves are often inverted in leads V1, V2, and V3 in children older than 1 month 1
  • Certain medications affect EKG findings, including antiarrhythmics, psychotropics, anti-infectives, antihypertensives, and heart failure medications 2, 3
  • Athletes may have normal variants like sinus bradycardia (≥30 beats/min) 1

Critical Pitfalls to Avoid

  • Never rely on computer interpretation without physician verification—errors in automated interpretation are common 1, 3
  • Avoid misplacement of electrodes, particularly precordial leads, which can cause false diagnoses 1
  • Do not interpret EKG findings in isolation without clinical context 1, 2
  • Always compare with previous EKGs when available to identify important changes 1
  • Ensure adequate filtering settings to avoid distorted waveforms 1
  • Verify recording quality and identify technical artifacts before interpretation 1, 3

Integration with Clinical Practice

  • Always interpret the EKG in context of the patient's symptoms—the same finding has different implications depending on clinical presentation 1, 2
  • Patients with cardiac symptoms (chest pain, dyspnea, palpitations, syncope) require EKG evaluation 4
  • A normal EKG in an asymptomatic patient generally does not require further cardiac testing 3
  • Repeat EKGs are warranted if patients develop new symptoms: syncope, changed chest pain pattern, worsening dyspnea, extreme fatigue, or palpitations 3

References

Guideline

EKG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

ECG Interpretation Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Normal Electrocardiogram Characteristics and Recommendations

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

The Electrocardiogram: Still a Useful Tool in the Primary Care Office.

The Medical clinics of North America, 2019

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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