Is a QRS (electrocardiogram complex) axis that is positive in lead I and lead II, and negative in lead aVF, indicative of a leftward axis?

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QRS Axis Interpretation: Positive in I and II, Negative in aVF

No, this is NOT a leftward axis—this pattern represents a normal axis between 0° and +60°. A leftward (left axis deviation) requires the axis to be between -30° and -90°, which would show a positive QRS in lead I but a negative QRS in lead II 1.

Understanding the Axis Quadrant System

The frontal plane axis is determined by analyzing QRS polarity in leads I and aVF, which are orthogonal (perpendicular) to each other in the hexaxial system 2:

  • Lead I at 0°: Positive QRS indicates axis is leftward (between -90° and +90°)
  • Lead aVF at +90°: Positive QRS indicates axis is inferior (between 0° and +180°)

Your Specific Pattern Analysis

With positive QRS in leads I and II, but negative in aVF, the axis falls in the normal range between 0° and +60° 2:

  • Positive lead I: Confirms the axis is somewhere between -90° and +90°
  • Positive lead II (at +60°): Indicates the axis has not deviated leftward past 0°
  • Negative lead aVF (at +90°): Indicates the axis is superior to +90°, narrowing the range to between 0° and +90°

Since lead II is positive, the axis must be between 0° and +60° (closer to lead II's orientation) 2.

Defining Left Axis Deviation

True left axis deviation requires the frontal plane axis to be between -45° and -90° 3, 1. The key distinguishing features are:

  • Positive QRS in lead I (present in your case)
  • Negative QRS in lead II (NOT present in your case—this is the critical difference)
  • Negative QRS in lead aVF (present in your case, but insufficient alone)

Common Clinical Pitfall

The most frequent error is assuming that a negative aVF alone indicates left axis deviation 2. Lead II polarity is the critical discriminator:

  • If lead II is positive with negative aVF → Normal axis (0° to +60°)
  • If lead II is negative with negative aVF → Left axis deviation (-30° to -90°) 1

When Left Axis Deviation Matters Clinically

Left axis deviation between -45° and -90° suggests left anterior fascicular block (LAFB) when accompanied by 3, 1:

  • QRS duration <120 ms
  • qR pattern in lead aVL
  • R-peak time in aVL ≥45 ms
  • rS pattern in leads II, III, and aVF

However, your pattern does not meet these criteria since lead II is positive 1.

References

Guideline

EKG Criteria for Left Anterior Fascicular Block

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

QRS axis validation in clinical electrocardiography.

The American journal of cardiology, 2008

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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