What are the benefits and risks of Ashwagandha (Withania somnifera)?

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From the Research

Ashwagandha is a beneficial adaptogenic herb that can help reduce stress and anxiety, improve sleep quality, and potentially boost testosterone levels in men, with a recommended dosage of 300-600mg daily of root extract, as supported by the most recent and highest quality study 1.

Benefits of Ashwagandha

  • Reduces stress and anxiety
  • Improves sleep quality
  • Potentially boosts testosterone levels in men
  • May help reduce inflammation and support immune function

Risks and Precautions

  • May cause digestive upset, drowsiness, and interact with medications for thyroid disorders, diabetes, high blood pressure, and immunosuppressants
  • Not recommended during pregnancy due to potential risk of miscarriage
  • People with autoimmune conditions like rheumatoid arthritis, lupus, or Hashimoto's thyroiditis should avoid ashwagandha as it may stimulate the immune system

Recommended Dosage

  • 300-600mg daily of root extract, often taken with food to minimize stomach discomfort
  • For stress reduction, studies typically use 300mg twice daily for 8-12 weeks

Mechanism of Action

  • Potentially regulates cortisol levels and modulates neurotransmitter function in the brain, explaining its stress-reducing properties

Important Considerations

  • Always consult with a healthcare provider before starting ashwagandha, especially if you have existing health conditions or take medications
  • The most recent and highest quality study 1 supports the use of ashwagandha for reducing stress and anxiety, with a significant reduction in anxiety and stress levels compared to placebo.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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