What is the recommended dose of Paracetamol (acetaminophen) for a 2-year-old child weighing 9.5kg?

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Paracetamol Dosing for 2-Year-Old Child (9.5 kg)

For a 2-year-old child weighing 9.5 kg, the recommended paracetamol dose is 5 mL (160 mg) every 4 hours, not to exceed 5 doses in 24 hours. 1

Weight-Based Dosing Category

  • This child falls into the "2 to under 4 years of age" category according to FDA labeling, which specifies 5 mL (160 mg) every 4 hours 1
  • At 9.5 kg, this child is in the lowest weight range for pediatric dosing, requiring careful adherence to labeled doses to prevent overdosage while maintaining therapeutic efficacy 2
  • The standard weight-based calculation for paracetamol is 10-15 mg/kg per dose, which would yield 95-142.5 mg per dose for this child, aligning well with the FDA-recommended 160 mg dose 1

Administration Guidelines

  • Maximum daily dose: 800 mg (5 doses of 160 mg each) in 24 hours 1
  • Administer every 4 hours as needed for fever or pain 1
  • The medication can be given with or without meals, though administration with food may improve gastrointestinal tolerability 2
  • Use the appropriate measuring device (oral syringe or dosing cup) to ensure accurate 5 mL measurement 1

Safety Considerations

  • Never exceed 5 doses in 24 hours to avoid hepatotoxicity risk 1
  • Children under 2 years are pharmacologically immature and require strict adherence to weight-based dosing 3
  • Paracetamol should be used at the lowest effective dosage and for the shortest time necessary 4
  • If fever or pain persists beyond 48-72 hours, reassess for alternative diagnoses rather than continuing prolonged paracetamol use 2

Common Pitfalls to Avoid

  • Do not use adult formulations or dosing schedules for pediatric patients 3
  • Avoid combining multiple paracetamol-containing products (e.g., cold medications that also contain paracetamol) as this increases overdose risk 5
  • Do not calculate doses based solely on age without considering weight, as the FDA label provides age-based guidance that assumes typical weight ranges 1

References

Guideline

Pediatric Medication Dosing Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Pediatric Medication Dosing Considerations

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Is acetaminophen safe in pregnancy?

Scandinavian journal of pain, 2017

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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