What is the recommended dose of Miralax (polyethylene glycol) for children?

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Miralax Dosing for Children

For children 17 years and older, the FDA-approved dose is 17 grams (one packet or capful) dissolved in 4-8 ounces of beverage once daily for up to 7 days, while children 16 years and under require physician consultation before use. 1

FDA-Approved Dosing by Age

Children 16 Years and Under

  • The FDA label explicitly states to "ask a doctor" before administering Miralax to children 16 years of age or under 1
  • This reflects that Miralax (polyethylene glycol 3350 without electrolytes) lacks FDA approval for pediatric use in this age group 1

Adolescents 17 Years and Older

  • Dose: 17 grams once daily 1
  • Mix one packet or capful in 4-8 ounces of any beverage (cold, hot, or room temperature) 1
  • Ensure powder is fully dissolved before drinking; do not drink if clumps remain 1
  • Maximum duration: 7 days without physician supervision 1

Evidence-Based Pediatric Dosing (Off-Label)

While not FDA-approved for children under 17, substantial research supports off-label use:

Infants Under 18 Months

  • Mean effective maintenance dose: 0.78 g/kg/day (range 0.26-1.26 g/kg/day) 2
  • A 2004 study demonstrated 97.6% efficacy in relieving constipation in 28 infants 2
  • Safety profile similar to older children, with only transient diarrhea requiring dose adjustment in some cases 2

Children 18 Months and Older

  • Typical dosing range: 0.4-3.8 sachets (approximately 6.8-64.6 grams) daily, depending on age and response 3
  • Age-specific ranges from a 2018 randomized controlled trial:
    • 0-2 years: 0.4-2.3 sachets daily 3
    • 2-4 years: 0.1-3.5 sachets daily 3
    • 4-8 years: 0.7-3.8 sachets daily 3
    • 8-16 years: 0.6-3.7 sachets daily 3

Important Safety Considerations

Administration Guidelines

  • Do not combine with starch-based thickeners used for swallowing difficulties 1
  • Ensure complete dissolution before consumption 1
  • Can be mixed in any temperature beverage for palatability 1

When to Seek Medical Guidance

  • All children 16 years and under require physician consultation before initiating therapy 1
  • Duration exceeding 7 days requires medical supervision 1
  • Dose adjustments should be made based on clinical response, particularly if diarrhea develops 2

Clinical Efficacy Notes

Long-term use (up to 52 weeks) has been studied in children, with treatment success (≥3 bowel movements per week with <1 fecal incontinence episode) achieved in approximately 45-50% of patients 3. The safety profile over this extended period showed no serious drug-related adverse events 3.

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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