What is the most appropriate management for a pregnant woman at 33 weeks gestation with severe abdominal pain, moderate vaginal bleeding, and hypotension, with a reassuring cardiotocography (CTG) tracing?

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Management of Hemodynamically Unstable Pregnant Woman at 33 Weeks with Ongoing Bleeding

Immediate cesarean section after one dose of dexamethasone is the most appropriate management for this patient, as maternal hemodynamic instability with ongoing bleeding constitutes an absolute indication for emergency delivery regardless of reassuring fetal monitoring. 1

Rationale for Immediate Delivery

The clinical presentation of hypotension with ongoing vaginal bleeding indicates maternal hemodynamic compromise that takes priority over all other considerations. 1 The European Society of Cardiology explicitly states that urgent delivery, irrespective of gestation, must be considered in women presenting with hemodynamic instability, with the primary consideration being maternal cardiovascular benefit. 2

Cesarean section is specifically preferred for women who are critically ill and hemodynamically unstable. 2 The American College of Obstetricians and Gynecologists reinforces that cesarean delivery should be performed for patients in acute intractable heart failure or hemodynamic instability. 1

Critical Pitfall to Avoid

The reassuring CTG is a dangerous distraction in this clinical scenario. Fetal monitoring should not delay maternal resuscitation and definitive management when the mother is hemodynamically unstable. 1 The ongoing bleeding despite admission indicates failure of conservative management and progressive maternal deterioration.

Corticosteroid Administration Protocol

A single dose of dexamethasone (12 mg IM) should be administered immediately for fetal lung maturation at 33 weeks gestation. 1 Maternal stability takes precedence, and delivery should NOT be delayed waiting for the second dose of steroids. 1

The optimal benefit occurs when delivery happens 24-48 hours after the first corticosteroid dose, but this must be balanced against maternal safety. 3, 4 In this hemodynamically unstable patient, the delay for steroid benefit is not justified. 1

Why Other Options Are Inappropriate

Blood Transfusion Alone

While blood transfusion will be necessary as part of resuscitation, it does not address the underlying source of bleeding and maternal instability. 5 Transfusion should occur concurrently with preparation for delivery, not as an alternative to it. 1

Induction of Labor

Induction of labor is contraindicated in a hemodynamically unstable patient with ongoing bleeding. 6 Labor would prolong the time to delivery, worsen maternal hemodynamic status, and increase the risk of maternal cardiovascular collapse. 2 Vaginal delivery is only appropriate when the maternal cardiac condition is well controlled. 2

Observation with Dexamethasone

Observation is inappropriate when the patient is hypotensive with ongoing bleeding. 1 The European Society of Cardiology states that unless there is deterioration in maternal condition, early delivery may not be needed—but this patient has ALREADY deteriorated with hypotension and ongoing bleeding. 2

Intraoperative Considerations

General anesthesia is preferred in hemodynamically unstable patients requiring immediate delivery, as regional anesthesia can worsen hypotension and is relatively contraindicated in hypovolemic shock. 1

Preparation for massive transfusion protocol with 1:1 ratio of RBC:FFP should be initiated. 1 Continuous hemodynamic monitoring should continue for at least 24 hours post-delivery due to significant fluid shifts. 2, 1

References

Guideline

Management of Hemodynamically Unstable Pregnant Women

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Guidelines for the Management of a Pregnant Trauma Patient.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC, 2015

Guideline

Timing of Delivery for Fetal Growth Restriction (FGR) with Abnormal Dopplers

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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