What is the recommended dosage of Tylenol (acetaminophen) for an 11-pound baby?

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Tylenol Dosage for 11-Pound Baby

For an 11-pound (5 kg) baby, give 50-75 mg of acetaminophen (Tylenol) every 4-6 hours as needed, using the 15 mg/kg dose which is most effective for infants. 1

Weight-Based Dosing Calculation

  • An 11-pound baby weighs 5 kg (11 lbs ÷ 2.2 = 5 kg)
  • Standard dosing is 10-15 mg/kg per dose 1
  • For a 5 kg infant:
    • 10 mg/kg = 50 mg per dose
    • 15 mg/kg = 75 mg per dose 1

The 15 mg/kg dose (75 mg) is preferred for infants under 10 kg, as pharmacokinetic modeling demonstrates that 10 mg/kg doses fail to reach therapeutic plasma concentrations (10-20 μg/mL) needed for effective antipyresis. 2, 3

Practical Administration

  • Using infant acetaminophen drops (160 mg/5 mL concentration):
    • For 50 mg: give 1.6 mL
    • For 75 mg: give 2.3 mL 1
  • Dosing interval: Every 4-6 hours as needed 1
  • Maximum: 5 doses in 24 hours (never exceed 60 mg/kg per day) 1

Critical Safety Considerations

For infants under 3 months of age, acetaminophen is the only recommended analgesic—ibuprofen should not be used. 1 This 11-pound baby is likely 2-4 months old based on typical growth patterns, making acetaminophen the appropriate choice.

Oral syrup formulation is absorbed more rapidly and provides more consistent response compared to rectal suppositories, which have erratic absorption. 1, 4 Use oral administration whenever possible.

Parents must ensure regular feeding to reduce hypoglycemia risk. If the infant becomes unwell and feeding is reduced, stop acetaminophen until normal feeding resumes. 5

Common Dosing Errors to Avoid

Up to 62% of parents give inaccurate acetaminophen doses, with infants under 1 year at highest risk for dosing errors. 6 The most common mistake is using age-based rather than weight-based dosing, which leads to underdosing in smaller infants. 2, 6

Weight-based dosing significantly reduces dosing errors compared to age-based recommendations. 6 Always calculate the dose based on the infant's actual weight in kilograms, not age or manufacturer's age-based charts.

Never use adult formulations or concentrations for infants, as this dramatically increases the risk of calculation errors and potential overdose. 1

References

Guideline

Pediatric Acetaminophen and Ibuprofen Dosing Guidelines

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Research

Pediatric dosing of acetaminophen.

Pediatric pharmacology (New York, N.Y.), 1983

Guideline

Injectable Paracetamol Dosing in Children

Praxis Medical Insights: Practical Summaries of Clinical Guidelines, 2025

Guideline

Guideline Directed Topic Overview

Dr.Oracle Medical Advisory Board & Editors, 2025

Research

Acetaminophen and ibuprofen dosing by parents.

Pediatric emergency care, 2000

Professional Medical Disclaimer

This information is intended for healthcare professionals. Any medical decision-making should rely on clinical judgment and independently verified information. The content provided herein does not replace professional discretion and should be considered supplementary to established clinical guidelines. Healthcare providers should verify all information against primary literature and current practice standards before application in patient care. Dr.Oracle assumes no liability for clinical decisions based on this content.

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